Showing entry for Sodium/potassium-transporting ATPase subunit alpha-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006471
Protein NameSodium/potassium-transporting ATPase subunit alpha-1
Uniport IdP06685
GeneAtp1a1
Gene Id24211
DomainCation_ATPase; Cation_ATPase_C; Cation_ATPase_N; E1-E2_ATPase
Pfam PF00689   PF00690  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0060048 cardiac muscle contraction
Biological Process GO:0030007 cellular potassium ion homeostasis
Biological Process GO:0071260 cellular response to mechanical stimulus
Biological Process GO:0071383 cellular response to steroid hormone stimulus
Biological Process GO:0006883 cellular sodium ion homeostasis
Biological Process GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient
Biological Process GO:0010248 establishment or maintenance of transmembrane electrochemical gradient
Biological Process GO:0060081 membrane hyperpolarization
Biological Process GO:0086009 membrane repolarization
Biological Process GO:0031947 negative regulation of glucocorticoid biosynthetic process
Biological Process GO:0045822 negative regulation of heart contraction
Biological Process GO:0045823 positive regulation of heart contraction
Biological Process GO:0045989 positive regulation of striated muscle contraction
Biological Process GO:1990573 potassium ion import across plasma membrane
Biological Process GO:0006813 potassium ion transport
Biological Process GO:1902600 proton transmembrane transport
Biological Process GO:0008217 regulation of blood pressure
Biological Process GO:0086004 regulation of cardiac muscle cell contraction
Biological Process GO:0002028 regulation of sodium ion transport
Biological Process GO:0002026 regulation of the force of heart contraction
Biological Process GO:0055119 relaxation of cardiac muscle
Biological Process GO:0042493 response to drug
Biological Process GO:1903416 response to glycoside
Biological Process GO:0036376 sodium ion export across plasma membrane
Biological Process GO:0006814 sodium ion transport
Biological Process GO:0055085 transmembrane transport
molecular function GO:0043531 ADP binding
molecular function GO:0030506 ankyrin binding
molecular function GO:0005524 ATP binding
molecular function GO:0051087 chaperone binding
molecular function GO:0016791 phosphatase activity
molecular function GO:0043548 phosphatidylinositol 3-kinase binding
molecular function GO:0030955 potassium ion binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0005391 sodium:potassium-exchanging ATPase activity
molecular function GO:0031402 sodium ion binding
molecular function GO:1990239 steroid hormone binding
cellular component GO:0016324 apical plasma membrane
cellular component GO:0030424 axon
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005901 caveola
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005768 endosome
cellular component GO:0005794 Golgi apparatus
cellular component GO:0016021 integral component of membrane
cellular component GO:0014704 intercalated disc
cellular component GO:0016328 lateral plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0031090 organelle membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0032991 protein-containing complex
cellular component GO:0042383 sarcolemma
cellular component GO:0005890 sodium:potassium-exchanging ATPase complex
cellular component GO:0036126 sperm flagellum
cellular component GO:0030315 T-tubule
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0023873 Ivermectin 874.51
BXGC0051524 Ouabain 584.28
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein