protein

Showing entry for Sodium/potassium-transporting ATPase subunit alpha-2

General Target Information
BXGT Id	BXGT006472
Protein Name	Sodium/potassium-transporting ATPase subunit alpha-2
Uniport Id	P06686
Gene	Atp1a2
Gene Id	24212
Domain	Cation_ATPase; Cation_ATPase_C; Cation_ATPase_N; E1-E2_ATPase; Hydrolase
Pfam	PF00689 PF00690
Organism	Rattus norvegicus (Rat)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0008344	adult locomotory behavior
Biological Process	GO:0021764	amygdala development
Biological Process	GO:0046034	ATP metabolic process
Biological Process	GO:0001662	behavioral fear response
Biological Process	GO:0060048	cardiac muscle contraction
Biological Process	GO:0098655	cation transmembrane transport
Biological Process	GO:0030007	cellular potassium ion homeostasis
Biological Process	GO:0071260	cellular response to mechanical stimulus
Biological Process	GO:0071383	cellular response to steroid hormone stimulus
Biological Process	GO:0006883	cellular sodium ion homeostasis
Biological Process	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient
Biological Process	GO:0040011	locomotion
Biological Process	GO:0035641	locomotory exploration behavior
Biological Process	GO:1903280	negative regulation of calcium:sodium antiporter activity
Biological Process	GO:1903170	negative regulation of calcium ion transmembrane transport
Biological Process	GO:0051481	negative regulation of cytosolic calcium ion concentration
Biological Process	GO:0045822	negative regulation of heart contraction
Biological Process	GO:0045988	negative regulation of striated muscle contraction
Biological Process	GO:0001504	neurotransmitter uptake
Biological Process	GO:0021989	olfactory cortex development
Biological Process	GO:1990573	potassium ion import across plasma membrane
Biological Process	GO:0071805	potassium ion transmembrane transport
Biological Process	GO:0006813	potassium ion transport
Biological Process	GO:1902600	proton transmembrane transport
Biological Process	GO:0008217	regulation of blood pressure
Biological Process	GO:0086004	regulation of cardiac muscle cell contraction
Biological Process	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
Biological Process	GO:0006937	regulation of muscle contraction
Biological Process	GO:0002087	regulation of respiratory gaseous exchange by nervous system process
Biological Process	GO:0006940	regulation of smooth muscle contraction
Biological Process	GO:0006942	regulation of striated muscle contraction
Biological Process	GO:0002026	regulation of the force of heart contraction
Biological Process	GO:0019229	regulation of vasoconstriction
Biological Process	GO:0055119	relaxation of cardiac muscle
Biological Process	GO:0010996	response to auditory stimulus
Biological Process	GO:1903416	response to glycoside
Biological Process	GO:0035094	response to nicotine
Biological Process	GO:0036376	sodium ion export across plasma membrane
Biological Process	GO:0035725	sodium ion transmembrane transport
Biological Process	GO:0006814	sodium ion transport
Biological Process	GO:0008542	visual learning
molecular function	GO:0016887	ATPase activity
molecular function	GO:0019829	ATPase-coupled cation transmembrane transporter activity
molecular function	GO:0005524	ATP binding
molecular function	GO:0051087	chaperone binding
molecular function	GO:0008144	drug binding
molecular function	GO:0030955	potassium ion binding
molecular function	GO:0046982	protein heterodimerization activity
molecular function	GO:0005391	sodium:potassium-exchanging ATPase activity
molecular function	GO:0031402	sodium ion binding
molecular function	GO:1990239	steroid hormone binding
cellular component	GO:0005901	caveola
cellular component	GO:0042995	cell projection
cellular component	GO:0005737	cytoplasm
cellular component	GO:0043197	dendritic spine
cellular component	GO:0005768	endosome
cellular component	GO:0014704	intercalated disc
cellular component	GO:0016020	membrane
cellular component	GO:0043025	neuronal cell body
cellular component	GO:0043005	neuron projection
cellular component	GO:0031090	organelle membrane
cellular component	GO:0005886	plasma membrane
cellular component	GO:0042383	sarcolemma
cellular component	GO:0005890	sodium:potassium-exchanging ATPase complex
cellular component	GO:0045202	synapse
cellular component	GO:0030315	T-tubule

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0022544	Digoxin		780.43
BXGC0051524	Ouabain		584.28

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}