Showing entry for Heme oxygenase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006501
Protein NameHeme oxygenase 1
Uniport IdP06762
GeneHmox1
Gene Id24451
DomainHeme_oxygenase
Pfam PF01126  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001525 angiogenesis
Biological Process GO:0008219 cell death
Biological Process GO:0006879 cellular iron ion homeostasis
Biological Process GO:0071243 cellular response to arsenic-containing substance
Biological Process GO:0071276 cellular response to cadmium ion
Biological Process GO:0072719 cellular response to cisplatin
Biological Process GO:0034605 cellular response to heat
Biological Process GO:0071456 cellular response to hypoxia
Biological Process GO:0031670 cellular response to nutrient
Biological Process GO:0034101 erythrocyte homeostasis
Biological Process GO:0042167 heme catabolic process
Biological Process GO:0042168 heme metabolic process
Biological Process GO:0006788 heme oxidation
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
Biological Process GO:0055072 iron ion homeostasis
Biological Process GO:0097421 liver regeneration
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0043392 negative regulation of DNA binding
Biological Process GO:0043433 negative regulation of DNA-binding transcription factor activity
Biological Process GO:1904036 negative regulation of epithelial cell apoptotic process
Biological Process GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
Biological Process GO:0016242 negative regulation of macroautophagy
Biological Process GO:0032764 negative regulation of mast cell cytokine production
Biological Process GO:0043305 negative regulation of mast cell degranulation
Biological Process GO:0010656 negative regulation of muscle cell apoptotic process
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:0048662 negative regulation of smooth muscle cell proliferation
Biological Process GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
Biological Process GO:0006644 phospholipid metabolic process
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
Biological Process GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
Biological Process GO:0016239 positive regulation of macroautophagy
Biological Process GO:0048661 positive regulation of smooth muscle cell proliferation
Biological Process GO:0008217 regulation of blood pressure
Biological Process GO:0051090 regulation of DNA-binding transcription factor activity
Biological Process GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron
Biological Process GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress
Biological Process GO:0042493 response to drug
Biological Process GO:0043627 response to estrogen
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0035094 response to nicotine
Biological Process GO:0006979 response to oxidative stress
Biological Process GO:0007264 small GTPase mediated signal transduction
Biological Process GO:0002246 wound healing involved in inflammatory response
molecular function GO:0019899 enzyme binding
molecular function GO:0020037 heme binding
molecular function GO:0004392 heme oxygenase (decyclizing) activity
molecular function GO:0042802 identical protein binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004630 phospholipase D activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0005198 structural molecule activity
cellular component GO:0005901 caveola
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0005730 nucleolus
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
BXGC0003751 Cyanide 26.02
BXGC0006368 Formic acid 46.03
BXGC0008676 Haem 616.49
BXGC0020706 Dithioerythritol 154.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein