Showing entry for ATP-dependent translocase ABCB1



                       
General Target Information
BXGT IdBXGT006507
Protein NameATP-dependent translocase ABCB1
Uniport IdP06795
GeneAbcb1b
Gene Id18669
DomainABC_membrane; ABC_tran
Pfam PF00664   PF00005  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0099040 ceramide translocation
Biological Process GO:0014045 establishment of endothelial blood-brain barrier
Biological Process GO:0045332 phospholipid translocation
Biological Process GO:0042493 response to drug
Biological Process GO:0061843 Sertoli cell barrier remodeling
molecular function GO:0016887 ATPase activity
molecular function GO:0042626 ATPase-coupled transmembrane transporter activity
molecular function GO:0008559 ATPase-coupled xenobiotic transmembrane transporter activity
molecular function GO:0005524 ATP binding
molecular function GO:0099038 ceramide floppase activity
molecular function GO:0140328 floppase activity
molecular function GO:0090554 phosphatidylcholine floppase activity
molecular function GO:0090555 phosphatidylethanolamine flippase activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0098591 external side of apical plasma membrane
cellular component GO:0000139 Golgi membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0046581 intercellular canaliculus
cellular component GO:0005739 mitochondrion
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002692 Arsenic 77.95
BXGC0022544 Digoxin 780.43
BXGC0024141 Hydrocortisone 362.21
BXGC0025658 Vinblastine 810.42
BXGC0030138 Colchicine 399.17
BXGC0030901 Morphine 285.14
BXGC0035201 Quinidine 324.18
BXGC0043126 Nicardipine 479.21
BXGC0044017 Verapamil 454.28
BXGC0052374 Reserpine 608.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein