Showing entry for Macrophage colony-stimulating factor 1



                       
General Target Information
BXGT IdBXGT006557
Protein NameMacrophage colony-stimulating factor 1
Uniport IdP07141
GeneCsf1
Gene Id12977
DomainCSF-1
Pfam PF05337  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0060444 branching involved in mammary gland duct morphogenesis
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0003006 developmental process involved in reproduction
Biological Process GO:0048873 homeostasis of number of cells within a tissue
Biological Process GO:0006954 inflammatory response
Biological Process GO:0045087 innate immune response
Biological Process GO:0038145 macrophage colony-stimulating factor signaling pathway
Biological Process GO:0030225 macrophage differentiation
Biological Process GO:0060763 mammary duct terminal end bud growth
Biological Process GO:0060611 mammary gland fat development
Biological Process GO:0061518 microglial cell proliferation
Biological Process GO:1901215 negative regulation of neuron death
Biological Process GO:0042476 odontogenesis
Biological Process GO:0001503 ossification
Biological Process GO:0030316 osteoclast differentiation
Biological Process GO:0002158 osteoclast proliferation
Biological Process GO:0001954 positive regulation of cell-matrix adhesion
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0032270 positive regulation of cellular protein metabolic process
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0010759 positive regulation of macrophage chemotaxis
Biological Process GO:1902228 positive regulation of macrophage colony-stimulating factor signaling pathway
Biological Process GO:0010744 positive regulation of macrophage derived foam cell differentiation
Biological Process GO:0045651 positive regulation of macrophage differentiation
Biological Process GO:1904141 positive regulation of microglial cell migration
Biological Process GO:0045657 positive regulation of monocyte differentiation
Biological Process GO:0032946 positive regulation of mononuclear cell proliferation
Biological Process GO:0040018 positive regulation of multicellular organism growth
Biological Process GO:0042488 positive regulation of odontogenesis of dentin-containing tooth
Biological Process GO:0045672 positive regulation of osteoclast differentiation
Biological Process GO:0045860 positive regulation of protein kinase activity
Biological Process GO:0046579 positive regulation of Ras protein signal transduction
Biological Process GO:0030278 regulation of ossification
Biological Process GO:0002931 response to ischemia
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
molecular function GO:0005125 cytokine activity
molecular function GO:0008083 growth factor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0005157 macrophage colony-stimulating factor receptor binding
molecular function GO:0042803 protein homodimerization activity
cellular component GO:1990682 CSF1-CSF1R complex
cellular component GO:0005615 extracellular space
cellular component GO:0016021 integral component of membrane
cellular component GO:0016604 nuclear body
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein