Showing entry for Complement component C8 gamma chain


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006613
Protein NameComplement component C8 gamma chain
Uniport IdP07360
GeneC8G
Gene Id733
DomainLipocalin
Pfam PF00061  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.1 Immune system hsa04610 Complement and coagulation cascades
6. Human Diseases 6.4 Neurodegenerative diseases hsa05020 Prion diseases
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05146 Amoebiasis
6. Human Diseases 6.3 Immune diseases hsa05322 Systemic lupus erythematosus
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006957 complement activation, alternative pathway
Biological Process GO:0006958 complement activation, classical pathway
Biological Process GO:0019835 cytolysis
Biological Process GO:0030449 regulation of complement activation
molecular function GO:0001848 complement binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0019841 retinol binding
cellular component GO:0072562 blood microparticle
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005579 membrane attack complex
Reactome
Pathway Id Pathway Name
R-HSA-166658 Complement cascade
R-HSA-166665 Terminal pathway of complement
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-977606 Regulation of Complement cascade
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0272242 BXGD006330 Complement deficiency disease Immune System Diseases; Hemic and Lymphatic Diseases
C2985280 BXGD018223 Blood Protein Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002248 Dodecanoic acid 200.32
BXGC0002682 Zinc 65.41
BXGC0003705 Chloride 35.45
BXGC0006198 Citric acid 192.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein