Showing entry for Bifunctional dihydrofolate reductase-thymidylate synthase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006618
Protein NameBifunctional dihydrofolate reductase-thymidylate synthase
Uniport IdP07382
GeneLmjF06.0860
Gene Id5649109
DomainDHFR_1; Thymidylat_synt
Pfam PF00186   PF00303  
OrganismLeishmania major
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006231 dTMP biosynthetic process
Biological Process GO:0032259 methylation
Biological Process GO:0006730 one-carbon metabolic process
Biological Process GO:0046654 tetrahydrofolate biosynthetic process
molecular function GO:0004146 dihydrofolate reductase activity
molecular function GO:0004799 thymidylate synthase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000558 1H-Indole-3-carboxaldehyde 145.16
BXGC0047867 Dalfampridine 94.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein