Showing entry for Serine hydroxymethyltransferase, cytosolic


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006632
Protein NameSerine hydroxymethyltransferase, cytosolic
Uniport IdP07511
GeneSHMT1
Gene Id100009405
DomainSHMT
Pfam PF00464  
OrganismOryctolagus cuniculus (Rabbit)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1904482 cellular response to tetrahydrofolate
Biological Process GO:0046655 folic acid metabolic process
Biological Process GO:0019264 glycine biosynthetic process from serine
Biological Process GO:0006544 glycine metabolic process
Biological Process GO:0006565 L-serine catabolic process
Biological Process GO:0006563 L-serine metabolic process
Biological Process GO:0051289 protein homotetramerization
Biological Process GO:0009113 purine nucleobase biosynthetic process
Biological Process GO:0035999 tetrahydrofolate interconversion
Biological Process GO:0046653 tetrahydrofolate metabolic process
molecular function GO:0004372 glycine hydroxymethyltransferase activity
molecular function GO:0048027 mRNA 5'-UTR binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0030170 pyridoxal phosphate binding
molecular function GO:0070905 serine binding
molecular function GO:0000900 translation repressor activity, mRNA regulatory element binding
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000226 Glycine 75.07
BXGC0000436 Glycerol 92.09
BXGC0043088 Pyridoxal Phosphate 247.02
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein