Showing entry for Aldo-keto reductase family 1 member B1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006700
Protein NameAldo-keto reductase family 1 member B1
Uniport IdP07943
GeneAkr1b1
Gene Id24192
DomainAldo_ket_red
Pfam PF00248  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071475 cellular hyperosmotic salinity response
Biological Process GO:0097238 cellular response to methylglyoxal
Biological Process GO:1901653 cellular response to peptide
Biological Process GO:0044597 daunorubicin metabolic process
Biological Process GO:0044598 doxorubicin metabolic process
Biological Process GO:0002070 epithelial cell maturation
Biological Process GO:0072061 inner medullary collecting duct development
Biological Process GO:0060135 maternal process involved in female pregnancy
Biological Process GO:0072205 metanephric collecting duct development
Biological Process GO:0005996 monosaccharide metabolic process
Biological Process GO:0018931 naphthalene metabolic process
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0042415 norepinephrine metabolic process
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
Biological Process GO:0048661 positive regulation of smooth muscle cell proliferation
Biological Process GO:0035809 regulation of urine volume
Biological Process GO:0003091 renal water homeostasis
Biological Process GO:0010033 response to organic substance
Biological Process GO:0097066 response to thyroid hormone
Biological Process GO:0009414 response to water deprivation
Biological Process GO:0001523 retinoid metabolic process
Biological Process GO:0006061 sorbitol biosynthetic process
Biological Process GO:0031098 stress-activated protein kinase signaling cascade
Biological Process GO:0001894 tissue homeostasis
molecular function GO:0008106 alcohol dehydrogenase (NADP+) activity
molecular function GO:0004032 alditol:NADP+ 1-oxidoreductase activity
molecular function GO:0047655 allyl-alcohol dehydrogenase activity
molecular function GO:0043795 glyceraldehyde oxidoreductase activity
molecular function GO:0052650 NADP-retinol dehydrogenase activity
molecular function GO:0016491 oxidoreductase activity
molecular function GO:0001758 retinal dehydrogenase activity
cellular component GO:0005829 cytosol
cellular component GO:0005615 extracellular space
cellular component GO:0042629 mast cell granule
cellular component GO:0005654 nucleoplasm
cellular component GO:0033010 paranodal junction
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0032838 plasma membrane bounded cell projection cytoplasm
cellular component GO:0043220 Schmidt-Lanterman incisure
cellular component GO:0097454 Schwann cell microvillus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000016 Butein 272.25
BXGC0000028 Apigenin 7-O-glucuronide 446.36
BXGC0000106 Cyclolariciresinol 360.4
BXGC0000130 Estradiol 272.38
BXGC0000202 Papaverine 339.39
BXGC0000204 Theophylline 180.16
BXGC0000226 Glycine 75.07
BXGC0000284 alpha-Tocopherol 430.71
BXGC0000286 L-DOPA 197.19
BXGC0000340 Kaempferol 286.24
BXGC0000396 4'-Hydroxy-3',5,6,7,8-pentamethoxyflavone 388.37
BXGC0000433 Triacetin 218.2
BXGC0000434 Ethanol 46.07
BXGC0000439 Chloroform 119.38
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0000528 Salicylic acid 138.12
BXGC0000536 Phenol 94.11
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0000622 Nicotinic acid 123.11
BXGC0000663 Papain 206.28
BXGC0000759 Arabinan 243.22
BXGC0000764 L-Ascorbic acid 176.12
BXGC0000894 2-Methylthioribosyl-trans-zeatin 323.8
BXGC0001000 4,8,5'-Trimethylpsoralen 228.24
BXGC0001002 1,2-Benzenediol 110.11
BXGC0001024 Cirsimaritin 314.29
BXGC0001166 Vitexin 6''-O-malonyl 2''-O-xyloside 432.38
BXGC0001273 Hippuric acid 179.17
BXGC0001325 Progesterone 314.46
BXGC0001502 Caffeine 194.19
BXGC0001550 Ficus Latex peptide 2 244.26
BXGC0001735 Axillarin 346.29
BXGC0001765 (E)-Resveratrol 3-glucoside 390.39
BXGC0001767 (E)-Resveratrol 228.25
BXGC0001837 Quercetin 3-rutinoside 610.52
BXGC0001868 Catechin 290.27
BXGC0001879 Chlorogenic acid 354.31
BXGC0001908 Demethoxysudachitin 330.29
BXGC0001918 3,5-Di-O-caffeoylquinic acid 516.45
BXGC0001919 4,5-Di-O-caffeoylquinic acid 516.45
BXGC0002012 (Z)-Isoeugenol 164.2
BXGC0002026 2-(3,4-Dihydroxyphenyl)-5,6-dihydroxy-7-methoxy-4H-1-benzopyran-4-one 316.26
BXGC0002030 Thymusin 330.29
BXGC0002031 Nevadensin 344.32
BXGC0002071 Apigenin 270.24
BXGC0002402 Ethyl carbamate 89.09
BXGC0002437 Lactic acid 90.08
BXGC0002441 Hydroxyacetic acid 76.05
BXGC0002627 17alpha-ethynylestradiol 296.4
BXGC0002690 alpha-Catechin 290.27
BXGC0002796 Nicotine 162.23
BXGC0002807 Spinosterol 412.7
BXGC0002853 beta-Amyrin 426.72
BXGC0002867 Lappaurin 284.74
BXGC0002906 Caffeic acid ester 284.31
BXGC0002916 Melatonin 232.28
BXGC0003048 Kaempferol 3-rhamno-glucoside 594.52
BXGC0003066 Phenols 199.27
BXGC0003131 N,N-Dimethylformamide 73.09
BXGC0003455 Isorhamnetin 3-beta-D-glucoside 478.4
BXGC0003501 Parthenolide 248.32
BXGC0003502 Phenylhydrazine 108.14
BXGC0003534 Mangiferol 422.34
BXGC0003546 Eugenyl glucoside 326.35
BXGC0003611 Latex 416.57
BXGC0003648 Majaronin 360.31
BXGC0003690 Glucokinin 764.94
BXGC0003707 Estrogen 268.36
BXGC0003773 Estriol 288.38
BXGC0003810 Cirsilion 330.29
BXGC0003948 8-Methoxycirsilineol 374.34
BXGC0003956 Fenugrin E 178.19
BXGC0004261 Propylene glycol 76.09
BXGC0004287 Allyl alcohol 58.08
BXGC0004556 1,2,3-Benzenetriol 126.11
BXGC0004560 Benzoic acid 122.12
BXGC0004565 Benzyl alcohol 108.14
BXGC0004587 (E)-3-Phenyl-2-propenal 132.16
BXGC0004712 Methylparaben 152.15
BXGC0005049 4-Methylumbelliferyl acetate 218.21
BXGC0005309 Hymenoxin 374.34
BXGC0005398 (-)-alpha-Narcotine 413.42
BXGC0005508 Safrole 162.19
BXGC0005624 Genistein 270.24
BXGC0005667 Quercitrin 448.38
BXGC0005683 Quercetin 302.24
BXGC0005702 2H-1-Benzopyran-2-one 146.15
BXGC0005879 Eugenol 164.2
BXGC0006105 Methyl salicylate 152.15
BXGC0006115 Xanthotoxin 216.19
BXGC0006125 Nicotinamide 122.12
BXGC0006156 Dicoumarol 336.3
BXGC0006193 Ellagic acid 302.19
BXGC0006198 Citric acid 192.12
BXGC0006300 5-Hydroxymethyl-2-furancarboxaldehyde 126.11
BXGC0006362 Estrone 270.37
BXGC0006366 trans-Ferulic acid 194.18
BXGC0006372 Ergocalciferol 396.65
BXGC0006389 Rotenone 394.42
BXGC0006422 Mercenene 214.05
BXGC0006635 Luteolin 286.24
BXGC0006982 Geraniol 154.25
BXGC0007601 1,8-Cineole 154.25
BXGC0008182 6-Hydroxyluteolin 302.24
BXGC0008707 Isoliquiritigenin 256.25
BXGC0008723 Sudachitin 360.31
BXGC0008753 Isoquercitrin 464.38
BXGC0008824 Astragalin 448.38
BXGC0008972 Cirsilineol 344.32
BXGC0008980 Xanthomicrol 344.32
BXGC0009542 Sideritiflavone 360.31
BXGC0009548 Epigallocatechin 306.27
BXGC0011489 4'-Hydroxy-5,6,7,8-tetramethoxyflavone 358.34
BXGC0012228 Vitamin D 384.64
BXGC0012243 Ukonan D 151.16
BXGC0012751 Regeol A 440.29
BXGC0012818 PRUNOSE I 712.22
BXGC0012834 29-hydroxyfriedelin 442.38
BXGC0013031 Demethylregelin 470.34
BXGC0013452 Dioctyl phthalate 390.28
BXGC0013582 Curcumin 368.13
BXGC0014695 Loratadine 382.14
BXGC0014895 Guajaverin 434.08
BXGC0015280 3Beta,22Beta-Dihydroxyolean-12-En-29-Oic Acid 472.36
BXGC0015492 Alcesefoliside 756.21
BXGC0015594 4-Nonylphenol 220.18
BXGC0015987 L-Mimosine 198.06
BXGC0016244 Nectandrin B 344.16
BXGC0016470 Camptothecin 348.11
BXGC0016548 30-Norhederagenin 456.32
BXGC0016671 Leucovorin 473.17
BXGC0016747 Camphor 152.12
BXGC0016891 Nortriptyline 263.17
BXGC0017115 Cephalexin 347.09
BXGC0017177 Vaticanol B 906.27
BXGC0017611 3',4'-Didemethylnobiletin 374.1
BXGC0017719 Strychnine 334.17
BXGC0018201 Beta-Amyrone 424.37
BXGC0018403 Hydroxyprogesterone 330.22
BXGC0018491 Methylprednisolone 374.21
BXGC0019011 Vaticanol A 680.2
BXGC0019074 benzoyloxypaeoniflorin 600.18
BXGC0019117 Tannic Acid 1700.17
BXGC0019164 Raloxifene 473.17
BXGC0020001 Quercetin 3-O-Neohesperidoside 610.15
BXGC0020171 (-)-Ampelopsin H 906.27
BXGC0020355 Fomepizole 82.05
BXGC0020800 Testosterone 288.21
BXGC0021077 Aconitine 645.31
BXGC0021478 Lipoic Acid 206.04
BXGC0022447 2-Naphthalen-1-Ylacetic Acid 186.07
BXGC0022544 Digoxin 780.43
BXGC0022593 3'-O-Methylquercetin3-O-Alpha-L-Rhamnopyranosyl(1->6)-2''-O-Acetyl-Beta-D-Glucopyranoside 666.18
BXGC0022673 Gymnasterkoreayne A 164.08
BXGC0022957 2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-3,8-Dimethoxychromen-4-One 346.07
BXGC0024079 5-Methoxyisolariciresinol 390.17
BXGC0024141 Hydrocortisone 362.21
BXGC0024177 orthosphenic acid 488.35
BXGC0024275 Paeonol 166.06
BXGC0024386 Atractyloside 724.21
BXGC0024413 Emetine 480.3
BXGC0024499 Chrysosplenol D 360.08
BXGC0024566 2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-8-Methoxychromen-4-One 316.06
BXGC0024642 triptotriterpenic acid C 472.36
BXGC0024729 Mercaptopurine 152.02
BXGC0024988 Nifedipine 346.12
BXGC0025357 22alpha-hydroxy-3-oxoolean-12-en-29-oic acid 470.34
BXGC0025658 Vinblastine 810.42
BXGC0026391 Naloxone 327.15
BXGC0026595 Glycyrrhizin 822.4
BXGC0026846 4-Hydroxy-trans-cinnamic acid (1S)-3beta-isopropyl-4beta-(beta-D-glucopyranosyloxy)-5,8abeta-dimethyl-8beta-hydroxy-1,2,3,4,4aalpha,7,8,8a-octahydronaphthalene-1beta-yl ester 562.28
BXGC0026968 1-(2-Hydroxy-4-Methoxyphenyl)-3-(4-Hydroxyphenyl)Prop-2-En-1-One 270.09
BXGC0027374 Glyburide 493.14
BXGC0027421 Paclitaxel 853.33
BXGC0027827 Tingenin B 436.26
BXGC0027854 Ethosuximide 141.08
BXGC0027975 (1R,10S)-10-Hydroxy-1,6,6-Trimethyl-10-(2-Oxopropyl)-1,2,6,7,8,9-Hexahydrophenanthro[1,2-B]Furan-11(10H)-One 354.18
BXGC0028196 Paeonolide 460.16
BXGC0028252 2-(3,4-Dihydroxyphenyl)-5,6,7-Trihydroxy-3-Methoxychromen-4-One 332.05
BXGC0028885 Secobarbital 238.13
BXGC0028916 Paeonoside 328.12
BXGC0028931 Vaticanol C 906.27
BXGC0029651 Isorhamnetin 3-O-Rhamnoside 462.12
BXGC0029722 2,2',4'-Trihydroxychalcone 256.07
BXGC0029761 Vaticanol B 906.27
BXGC0029826 (-)-Hopeaphenol 906.27
BXGC0030138 Colchicine 399.17
BXGC0030206 triptotriterpenic acid A 472.36
BXGC0030564 (+)-Lyoniresinol 420.18
BXGC0030600 Triptocalline A 442.31
BXGC0030663 Metformin 129.1
BXGC0030685 Physostigmine 275.16
BXGC0030900 Paeonoside 460.16
BXGC0031078 Hemsleyanol D 906.27
BXGC0031339 Clovandiol 238.19
BXGC0031384 Epinephrine 183.09
BXGC0031622 Podofilox 414.13
BXGC0032368 Sparteine 234.21
BXGC0032381 Daucosterol 576.44
BXGC0032568 huazhongilexin 436.17
BXGC0033776 Cycloheximide 281.16
BXGC0034035 Capsaicin 305.2
BXGC0034676 Wilfolic acid C 472.36
BXGC0034768 Vincristine 824.4
BXGC0034778 Artemisinin 282.15
BXGC0034783 Doxorubicin 543.17
BXGC0034956 (E)-1-(2,4-Dihydroxyphenyl)-3-(4-Methoxyphenyl)Prop-2-En-1-One 270.09
BXGC0035519 Amygdalin 457.16
BXGC0035692 2,2',4,4'-Tetrahydroxychalcone 272.07
BXGC0036254 Salaspermic Acid 472.36
BXGC0036544 Celahin C 532.23
BXGC0037076 bidenoside C 310.14
BXGC0037311 Apigenin-7-O-Beta-D-Glucuronide Methyl Ester 460.1
BXGC0037499 Palbinone 358.21
BXGC0037599 Tanshinone Iia 294.13
BXGC0037718 Ethacrynic Acid 302.01
BXGC0037782 Tetrahydrofuroguaiacin B 344.16
BXGC0038381 Tingenone 420.27
BXGC0038963 Dichlorvos 219.95
BXGC0039322 oxypaeoniflora 496.16
BXGC0039472 Narcissin 624.17
BXGC0039601 Levocarnitine 161.11
BXGC0039684 Berberine Chloride 336.12
BXGC0039787 2',4'-Dihydroxychalcone 240.08
BXGC0040042 Warfarin 308.1
BXGC0040462 Aminosalicylic Acid 153.04
BXGC0040705 Paeoniflorin 480.16
BXGC0041021 Quercetin 3,7-Dimethyl Ether 346.07
BXGC0041240 Atenolol 266.16
BXGC0041510 (1R,10S)-10-Hydroxy-1,6-Dimethyl-10-(2-Oxopropyl)-1,2-Dihydronaphtho[1,2-G][1]Benzofuran-11-One 336.14
BXGC0041927 Maytenoic Acid 456.36
BXGC0042127 Oxyquinoline 145.05
BXGC0042179 Atropine 289.17
BXGC0042180 Quercetin 3-O-Rhamnopyranoside 448.1
BXGC0042206 Danshenxinkun A 296.1
BXGC0042211 4-Octylphenol 206.17
BXGC0042222 Propranolol 259.16
BXGC0042339 Terbutaline 225.14
BXGC0042452 Panthenol 205.13
BXGC0042510 Fluoxetine 309.13
BXGC0042519 Glimepiride 490.22
BXGC0042596 Isoniazid 137.06
BXGC0042747 benzoylpaeoniflorin 584.19
BXGC0043648 (-)-Camphor 152.12
BXGC0043834 (S)-2-((2S,3S)-4-(3-((R)-1-Carboxy-2-(3,4-Dihydroxyphenyl)Ethoxy)-3-Oxoprop-1-Enyl)-2-(3,4-Dihydroxyphenyl)-7-Hydroxy-2,3-Dihydrobenzofuran-3-Carbonyloxy)-3-(3,4-Dihydroxyphenyl)Propanoic Acid 718.15
BXGC0044015 D0Z3FX 494.11
BXGC0044017 Verapamil 454.28
BXGC0044468 Ergosterol Peroxide 428.33
BXGC0044659 4-O-butylpaeoniflorin 536.23
BXGC0044663 8-O-benzoylpaeonidanin 584.23
BXGC0044666 nudanpinoside H 600.18
BXGC0044667 benzoyloxypaeoniflorin 600.18
BXGC0044688 6-methoxypaeoniflorigenone 332.13
BXGC0044810 Lamivudine 229.05
BXGC0044919 n.a 576.29
BXGC0044920 (2R)-2alpha-[1-(beta-D-Glucopyranosyloxymethyl)ethenyl]-3beta-methoxy-6-(1-oxoethyl)-2,3-dihydrobenzofuran-5-ol 426.15
BXGC0045812 Trifluoperazine 407.16
BXGC0046139 Aminoglutethimide 232.12
BXGC0046755 Yohimbine 354.19
BXGC0046862 Benzo[Def]Chrysene 252.09
BXGC0046996 Thioguanine 167.03
BXGC0047126 Artemether 298.18
BXGC0047169 Hymecromone 176.05
BXGC0047877 Mangiferin 438.08
BXGC0047923 Cirsimarin 476.13
BXGC0048313 Rosmarinic Acid 360.08
BXGC0048344 Prunose II 670.21
BXGC0049146 Phenylisothiocyanate 135.01
BXGC0049384 15alpha-hydroxyfriedelan-3-one 442.38
BXGC0049391 Betadex 1134.37
BXGC0049738 Dexibuprofen 206.13
BXGC0049862 alpha-viniferin 678.19
BXGC0050471 Fluorouracil 130.02
BXGC0050651 Cryptotanshinone 296.14
BXGC0050711 Paeoniflorigenone 318.11
BXGC0050816 Galantamine 287.15
BXGC0051133 Galloylpaeoniflorin 632.17
BXGC0051524 Ouabain 584.28
BXGC0051982 Mannitol 182.08
BXGC0052021 (R)-Ibuprophen 206.13
BXGC0052265 Erigeroflavanone 406.09
BXGC0052374 Reserpine 608.27
BXGC0052397 3-O-Alpha-L-Rhamnopyranosyl(1->6)-2''-O-Acetyl-Beta-D-Glucopyranoside 652.16
BXGC0052878 Bisphenol A 228.12
BXGC0052948 Tanshinone I 276.08
BXGC0053010 GYMNASTERKOREAYNE E 276.17
BXGC0053118 Streptomycin 581.27
BXGC0053261 Antimycin A 548.27
BXGC0053425 5-hydroxy-3S-hydroxymethyl-6-methyl-2,3-dihydrobenzofuran 180.08
BXGC0053767 Dihydrotanshinone I 278.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein