Showing entry for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006704
Protein Name6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
Uniport IdP07953
GenePfkfb1
Gene Id24638
Domain6PF2K; His_Phos_1
Pfam PF01591   PF00300  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031100 animal organ regeneration
Biological Process GO:0046835 carbohydrate phosphorylation
Biological Process GO:0006003 fructose 2,6-bisphosphate metabolic process
Biological Process GO:0006000 fructose metabolic process
Biological Process GO:0033133 positive regulation of glucokinase activity
Biological Process GO:0051591 response to cAMP
Biological Process GO:0033762 response to glucagon
Biological Process GO:0051384 response to glucocorticoid
Biological Process GO:0032868 response to insulin
Biological Process GO:0042594 response to starvation
molecular function GO:0003873 6-phosphofructo-2-kinase activity
molecular function GO:0005524 ATP binding
molecular function GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity
molecular function GO:0070095 fructose-6-phosphate binding
molecular function GO:0042802 identical protein binding
molecular function GO:0019900 kinase binding
cellular component GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001097 D-Glyceraldehyde 3-phosphate 170.06
BXGC0042541 fructose-6-phosphate 260.03
BXGC0048845 Guanosine Triphosphate 522.99
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein