protein

Showing entry for Dihydrofolate synthase/folylpolyglutamate synthase

　　　　　　　　　　　　

General Target Information
BXGT Id	BXGT006744
Protein Name	Dihydrofolate synthase/folylpolyglutamate synthase
Uniport Id	P08192
Gene	folC
Gene Id	945451
Domain	Mur_ligase_C; Mur_ligase_M
Pfam	PF02875 PF08245
Organism	Escherichia coli (strain K12)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0046656	folic acid biosynthetic process
Biological Process	GO:0009396	folic acid-containing compound biosynthetic process
Biological Process	GO:0006730	one-carbon metabolic process
Biological Process	GO:0046654	tetrahydrofolate biosynthetic process
molecular function	GO:0005524	ATP binding
molecular function	GO:0008841	dihydrofolate synthase activity
molecular function	GO:0046872	metal ion binding
molecular function	GO:0004326	tetrahydrofolylpolyglutamate synthase activity
cellular component	GO:0005737	cytoplasm

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002588	Magnesium		24.31
BXGC0007530	Folic acid		441.4
BXGC0035994	5-methyltetrahydrofolate		459.19

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}