Showing entry for Signal recognition particle receptor subunit alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006754
Protein NameSignal recognition particle receptor subunit alpha
Uniport IdP08240
GeneSRPRA
Gene Id6734
DomainSRP-alpha_N; SRP54; SRP54_N
Pfam PF04086   PF00448   PF02881  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa03060 Protein export
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006613 cotranslational protein targeting to membrane
Biological Process GO:0036498 IRE1-mediated unfolded protein response
Biological Process GO:0006605 protein targeting
Biological Process GO:0045047 protein targeting to ER
Biological Process GO:0006614 SRP-dependent cotranslational protein targeting to membrane
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0003723 RNA binding
molecular function GO:0005047 signal recognition particle binding
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0016020 membrane
cellular component GO:0005785 signal recognition particle receptor complex
Reactome
Pathway Id Pathway Name
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-381038 XBP1(S) activates chaperone genes
R-HSA-381070 IRE1alpha activates chaperones
R-HSA-381119 Unfolded Protein Response (UPR)
R-HSA-392499 Metabolism of proteins
R-HSA-392499 Metabolism of proteins
R-HSA-72766 Translation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0267375 BXGD005742 Chronic colitis Digestive System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein