Showing entry for Muscarinic acetylcholine receptor M3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006776
Protein NameMuscarinic acetylcholine receptor M3
Uniport IdP08483
GeneChrm3
Gene Id24260
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0095500 acetylcholine receptor signaling pathway
Biological Process GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway
Biological Process GO:0019722 calcium-mediated signaling
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0007213 G protein-coupled acetylcholine receptor signaling pathway
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
Biological Process GO:0045987 positive regulation of smooth muscle contraction
Biological Process GO:1904695 positive regulation of vascular associated smooth muscle contraction
Biological Process GO:0032412 regulation of ion transmembrane transporter activity
Biological Process GO:0003056 regulation of vascular associated smooth muscle contraction
Biological Process GO:0019229 regulation of vasoconstriction
Biological Process GO:0046541 saliva secretion
Biological Process GO:0006939 smooth muscle contraction
Biological Process GO:0007271 synaptic transmission, cholinergic
molecular function GO:0042166 acetylcholine binding
molecular function GO:0008144 drug binding
molecular function GO:0016907 G protein-coupled acetylcholine receptor activity
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0004993 G protein-coupled serotonin receptor activity
molecular function GO:0030594 neurotransmitter receptor activity
cellular component GO:0032279 asymmetric synapse
cellular component GO:0043679 axon terminus
cellular component GO:0009925 basal plasma membrane
cellular component GO:0030425 dendrite
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099061 integral component of postsynaptic density membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0016020 membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001589 Arecoline 155.19
BXGC0002796 Nicotine 162.23
BXGC0002852 Atropine 289.37
BXGC0003102 Acetylcholine 146.21
BXGC0014455 Fanchinin 622.3
BXGC0031080 Scopolamine 303.15
BXGC0039319 Muscarine 174.15
BXGC0042114 Solifenacin 362.2
BXGC0042179 Atropine 289.17
BXGC0046737 Berbamine 608.29
BXGC0046755 Yohimbine 354.19
BXGC0048924 homatropine 275.15
BXGC0051660 Endo-Atropine 289.17
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein