Showing entry for Genome polyprotein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006799
Protein NameGenome polyprotein
Uniport IdP08617
Gene
Gene Id1493918;1493919
DomainHAV_VP; Peptidase_C3; RdRP_1; Rhv; RNA_helicase
Pfam PF12944   PF00548   PF00680   PF00073   PF00910  
OrganismHuman hepatitis A virus genotype IB (isolate HM175) (HHAV) (Human hepatitis A virus (isolate Human/Australia/HM175/1976))
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034140 negative regulation of toll-like receptor 3 signaling pathway
Biological Process GO:0039707 pore formation by virus in membrane of host cell
Biological Process GO:0051259 protein complex oligomerization
Biological Process GO:0018144 RNA-protein covalent cross-linking
Biological Process GO:0039545 suppression by virus of host MAVS activity
Biological Process GO:0006351 transcription, DNA-templated
Biological Process GO:0046718 viral entry into host cell
Biological Process GO:0039694 viral RNA genome replication
Biological Process GO:0019068 virion assembly
Biological Process GO:0019062 virion attachment to host cell
molecular function GO:0005524 ATP binding
molecular function GO:0004197 cysteine-type endopeptidase activity
molecular function GO:0005216 ion channel activity
molecular function GO:0003723 RNA binding
molecular function GO:0003968 RNA-directed 5'-3' RNA polymerase activity
molecular function GO:0003724 RNA helicase activity
molecular function GO:0005198 structural molecule activity
cellular component GO:0044162 host cell cytoplasmic vesicle membrane
cellular component GO:0044193 host cell mitochondrial outer membrane
cellular component GO:0072494 host multivesicular body
cellular component GO:0019030 icosahedral viral capsid
cellular component GO:0016021 integral component of membrane
cellular component GO:0044385 integral to membrane of host cell
cellular component GO:0039618 T=pseudo3 icosahedral viral capsid
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein