Showing entry for 5-hydroxytryptamine receptor 2C


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006838
Protein Name5-hydroxytryptamine receptor 2C
Uniport IdP08909
GeneHtr2c
Gene Id25187
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031100 animal organ regeneration
Biological Process GO:0001662 behavioral fear response
Biological Process GO:0035095 behavioral response to nicotine
Biological Process GO:0006874 cellular calcium ion homeostasis
Biological Process GO:0019934 cGMP-mediated signaling
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0007631 feeding behavior
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
Biological Process GO:0048016 inositol phosphate-mediated signaling
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0045963 negative regulation of dopamine metabolic process
Biological Process GO:0040013 negative regulation of locomotion
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007208 phospholipase C-activating serotonin receptor signaling pathway
Biological Process GO:0031583 phospholipase D-activating G protein-coupled receptor signaling pathway
Biological Process GO:0014057 positive regulation of acetylcholine secretion, neurotransmission
Biological Process GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0045600 positive regulation of fat cell differentiation
Biological Process GO:0014054 positive regulation of gamma-aminobutyric acid secretion
Biological Process GO:0010513 positive regulation of phosphatidylinositol biosynthetic process
Biological Process GO:0045907 positive regulation of vasoconstriction
Biological Process GO:0032098 regulation of appetite
Biological Process GO:0043397 regulation of corticotropin-releasing hormone secretion
Biological Process GO:0031644 regulation of nervous system process
Biological Process GO:0051930 regulation of sensory perception of pain
Biological Process GO:0051209 release of sequestered calcium ion into cytosol
Biological Process GO:0042493 response to drug
Biological Process GO:0007210 serotonin receptor signaling pathway
molecular function GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
molecular function GO:0008144 drug binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0004993 G protein-coupled serotonin receptor activity
molecular function GO:0001587 Gq/11-coupled serotonin receptor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0051378 serotonin binding
cellular component GO:0009986 cell surface
cellular component GO:0030425 dendrite
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000191 Tyramine 137.18
BXGC0000226 Glycine 75.07
BXGC0000538 (R)-Norepinephrine 169.18
BXGC0000548 Tryptamine 160.22
BXGC0000982 L-Homocysteine 135.19
BXGC0001327 Nonacosan-8-one 165.23
BXGC0003102 Acetylcholine 146.21
BXGC0003196 Aripiprazole 448.39
BXGC0004665 4-Aminobutyric acid 103.12
BXGC0004757 2-Aminoacetophenone 135.16
BXGC0004760 2-Phenylethylamine 121.18
BXGC0005683 Quercetin 302.24
BXGC0005867 Serotonin 176.22
BXGC0005871 Dopamine 153.18
BXGC0005874 Racemethionine 149.21
BXGC0006109 2-Aminoquinoline 144.17
BXGC0006162 L-Glutamic acid 147.13
BXGC0006183 L-Cystine 240.3
BXGC0009318 Nb-Methylserotonin 190.24
BXGC0013070 Mescaline 211.12
BXGC0014068 Amphetamine 135.1
BXGC0016891 Nortriptyline 263.17
BXGC0020654 Dopa 197.07
BXGC0021893 Norepinephrine 169.07
BXGC0022192 Bufotenine 204.13
BXGC0026443 (S)-2-Amino-1-phenylethanol 137.08
BXGC0027950 1-(2,3-Dimethoxyphenyl)Propan-2-Amine 195.13
BXGC0028943 1-(3-Methoxyphenyl)Propan-2-Amine 165.12
BXGC0032808 cathinone 149.08
BXGC0034989 N-Methylmescaline 225.14
BXGC0035358 1-(4-Ethoxyphenyl)Propan-2-Amine 179.13
BXGC0038837 Pseudohypericin 520.08
BXGC0038892 (1R,2S)-Phenylpropanolamine 151.1
BXGC0038909 1-(4-methylphenyl)propane-2-amine 149.12
BXGC0038980 cathinone 149.08
BXGC0039091 1-(3,4,5-Trimethoxyphenyl)Propan-2-Amine 225.14
BXGC0042222 Propranolol 259.16
BXGC0042462 Cysteine 121.02
BXGC0042510 Fluoxetine 309.13
BXGC0043954 2-(4-Methoxyphenyl)Ethanamine 151.1
BXGC0045812 Trifluoperazine 407.16
BXGC0046755 Yohimbine 354.19
BXGC0050172 N,N-Dimethyltryptamine 188.13
BXGC0050611 5-Methoxy-N-Methyltryptamine 204.13
BXGC0052374 Reserpine 608.27
BXGC0052798 5-Meo-Dmt 218.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein