Showing entry for Protein toll


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006844
Protein NameProtein toll
Uniport IdP08953
GeneTl
Gene Id43222
DomainLRRNT; LRR_1; LRR_8; TIR
Pfam PF00560   PF13306   PF13855   PF01462   PF01582  
OrganismDrosophila melanogaster (Fruit fly)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0061760 antifungal innate immune response
Biological Process GO:0007155 cell adhesion
Biological Process GO:0035212 cell competition in a multicellular organism
Biological Process GO:0050830 defense response to Gram-positive bacterium
Biological Process GO:0002229 defense response to oomycetes
Biological Process GO:0009597 detection of virus
Biological Process GO:0009950 dorsal/ventral axis specification
Biological Process GO:0007507 heart development
Biological Process GO:0045087 innate immune response
Biological Process GO:0007526 larval somatic muscle development
Biological Process GO:0030308 negative regulation of cell growth
Biological Process GO:0040015 negative regulation of multicellular organism growth
Biological Process GO:0002804 positive regulation of antifungal peptide production
Biological Process GO:0002225 positive regulation of antimicrobial peptide production
Biological Process GO:0035208 positive regulation of hemocyte proliferation
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:1902875 regulation of embryonic pattern specification
Biological Process GO:0002347 response to tumor cell
Biological Process GO:0009611 response to wounding
Biological Process GO:0007416 synapse assembly
Biological Process GO:0016201 synaptic target inhibition
Biological Process GO:0002224 toll-like receptor signaling pathway
Biological Process GO:0008063 Toll signaling pathway
molecular function GO:0019955 cytokine binding
molecular function GO:0004896 cytokine receptor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0050135 NAD(P)+ nucleosidase activity
molecular function GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
molecular function GO:0038023 signaling receptor activity
molecular function GO:0070976 TIR domain binding
molecular function GO:0004888 transmembrane signaling receptor activity
molecular function GO:0046790 virion binding
cellular component GO:0009986 cell surface
cellular component GO:0032154 cleavage furrow
cellular component GO:0005769 early endosome
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0018397 beta-1,4-mannan 180.06
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein