Showing entry for Protein kinase C zeta type


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006872
Protein NameProtein kinase C zeta type
Uniport IdP09217
GenePrkcz
Gene Id25522
DomainC1_1; PB1; Pkinase; Pkinase_C
Pfam PF00130   PF00564   PF00069   PF00433  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031584 activation of phospholipase D activity
Biological Process GO:0032148 activation of protein kinase B activity
Biological Process GO:0016477 cell migration
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:0034613 cellular protein localization
Biological Process GO:0032869 cellular response to insulin stimulus
Biological Process GO:0030010 establishment of cell polarity
Biological Process GO:0006954 inflammatory response
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0007616 long-term memory
Biological Process GO:0060291 long-term synaptic potentiation
Biological Process GO:0051899 membrane depolarization
Biological Process GO:0060081 membrane hyperpolarization
Biological Process GO:0000226 microtubule cytoskeleton organization
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0051346 negative regulation of hydrolase activity
Biological Process GO:0046627 negative regulation of insulin receptor signaling pathway
Biological Process GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0031333 negative regulation of protein-containing complex assembly
Biological Process GO:1990138 neuron projection extension
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0001954 positive regulation of cell-matrix adhesion
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:2000463 positive regulation of excitatory postsynaptic potential
Biological Process GO:0046628 positive regulation of insulin receptor signaling pathway
Biological Process GO:0032733 positive regulation of interleukin-10 production
Biological Process GO:0032736 positive regulation of interleukin-13 production
Biological Process GO:0032753 positive regulation of interleukin-4 production
Biological Process GO:0032754 positive regulation of interleukin-5 production
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:0051222 positive regulation of protein transport
Biological Process GO:0050806 positive regulation of synaptic transmission
Biological Process GO:2000553 positive regulation of T-helper 2 cell cytokine production
Biological Process GO:0045630 positive regulation of T-helper 2 cell differentiation
Biological Process GO:0070528 protein kinase C signaling
Biological Process GO:0072659 protein localization to plasma membrane
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0007165 signal transduction
Biological Process GO:0047496 vesicle transport along microtubule
molecular function GO:0071889 14-3-3 protein binding
molecular function GO:0005524 ATP binding
molecular function GO:0004698 calcium-dependent protein kinase C activity
molecular function GO:0046872 metal ion binding
molecular function GO:0043274 phospholipase binding
molecular function GO:0015459 potassium channel regulator activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0004697 protein kinase C activity
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0045179 apical cortex
cellular component GO:0016324 apical plasma membrane
cellular component GO:0043203 axon hillock
cellular component GO:0005923 bicellular tight junction
cellular component GO:0005911 cell-cell junction
cellular component GO:0005938 cell cortex
cellular component GO:0031252 cell leading edge
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005768 endosome
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0045121 membrane raft
cellular component GO:0005815 microtubule organizing center
cellular component GO:0035748 myelin sheath abaxonal region
cellular component GO:0005635 nuclear envelope
cellular component GO:0016363 nuclear matrix
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0001725 stress fiber
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000759 Arabinan 243.22
BXGC0001765 (E)-Resveratrol 3-glucoside 390.39
BXGC0001767 (E)-Resveratrol 228.25
BXGC0002579 (Z)-Resveratrol 3-glucoside 390.38
BXGC0002961 Thiophen-3-carboxyaldehyde 112.15
BXGC0003364 Cerebroside 299.49
BXGC0003772 Corilagin 634.45
BXGC0006057 (Z)-Resveratrol 228.25
BXGC0007052 Olomoucine 298.34
BXGC0021390 n.a 390.13
BXGC0025876 Acetoside 624.21
BXGC0034756 3,5,4'-trihydroxystilbene-4'-O-glucoside 390.13
BXGC0044194 Punicafolin 938.1
BXGC0045812 Trifluoperazine 407.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein