Showing entry for Interferon-induced protein with tetratricopeptide repeats 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006940
Protein NameInterferon-induced protein with tetratricopeptide repeats 1
Uniport IdP09914
GeneIFIT1
Gene Id3434
DomainTPR_12; TPR_8
Pfam PF13181  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.9 Infectious diseases: Viral hsa05160 Hepatitis C
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071360 cellular response to exogenous dsRNA
Biological Process GO:0071357 cellular response to type I interferon
Biological Process GO:0051607 defense response to virus
Biological Process GO:0019060 intracellular transport of viral protein in host cell
Biological Process GO:0051097 negative regulation of helicase activity
Biological Process GO:0032091 negative regulation of protein binding
Biological Process GO:0045071 negative regulation of viral genome replication
Biological Process GO:0045070 positive regulation of viral genome replication
Biological Process GO:0050688 regulation of defense response to virus
Biological Process GO:0009615 response to virus
Biological Process GO:0060337 type I interferon signaling pathway
Biological Process GO:0016032 viral process
molecular function GO:0003723 RNA binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0043657 host cell
Reactome
Pathway Id Pathway Name
R-HSA-1169408 ISG15 antiviral mechanism
R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-168256 Immune System
R-HSA-909733 Interferon alpha/beta signaling
R-HSA-913531 Interferon Signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0006271 BXGD000384 Bronchiolitis Infections; Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0027092 BXGD001971 Myopia Eye Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030389 BXGD002216 Parainfluenza Infections
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0085293 BXGD003154 Hepatitis E Digestive System Diseases; Infections
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206633 BXGD004198 Angiomyolipoma Neoplasms
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0276289 BXGD006418 Zika Virus Infection Infections
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0375023 BXGD007970 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
C0867389 BXGD011300 Chronic graft-versus-host disease Immune System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2062441 BXGD016897 Influenza A
C3264382 BXGD018591 Swine influenza virus (viruses that normally cause infections in pigs)
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3714514 BXGD019409 Infection Infections
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein