Showing entry for Replicase polyprotein 1ab


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007443
Protein NameReplicase polyprotein 1ab
Uniport IdP0C6Y5
Generep
Gene Id
DomainA_30; CNV-Replicase_N; Corona_NSP4_C; Corona_RPol_N; Macro; NSP10; NSP11; NSP16; nsp7; nsp8; nsp9; Peptidase_C30; Viral_protease
Pfam PF13087   PF16688   PF16348   PF06478   PF01661   PF09401   PF06471   PF06460   PF08716   PF08717   PF08710   PF05409   PF08715  
OrganismPorcine transmissible gastroenteritis coronavirus (strain Purdue) (TGEV)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0039520 induction by virus of host autophagy
Biological Process GO:0032259 methylation
Biological Process GO:0039648 modulation by virus of host protein ubiquitination
Biological Process GO:0039548 suppression by virus of host IRF3 activity
Biological Process GO:0006351 transcription, DNA-templated
Biological Process GO:0019079 viral genome replication
Biological Process GO:0019082 viral protein processing
molecular function GO:0005524 ATP binding
molecular function GO:0004197 cysteine-type endopeptidase activity
molecular function GO:0003678 DNA helicase activity
molecular function GO:0004519 endonuclease activity
molecular function GO:0004527 exonuclease activity
molecular function GO:0008168 methyltransferase activity
molecular function GO:0003723 RNA binding
molecular function GO:0003968 RNA-directed 5'-3' RNA polymerase activity
molecular function GO:0003724 RNA helicase activity
molecular function GO:0036459 thiol-dependent ubiquitinyl hydrolase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0044172 host cell endoplasmic reticulum-Golgi intermediate compartment
cellular component GO:0033644 host cell membrane
cellular component GO:0044220 host cell perinuclear region of cytoplasm
cellular component GO:0016021 integral component of membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042315 1,4-dioxane 88.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein