Showing entry for Botulinum neurotoxin type A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007528
Protein NameBotulinum neurotoxin type A
Uniport IdP0DPI0
GenebotA
Gene Id
Domain-
Pfam PF01742   PF07951   PF07953   PF07952  
OrganismClostridium botulinum
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046929 negative regulation of neurotransmitter secretion
Biological Process GO:0009405 pathogenesis
molecular function GO:1905576 ganglioside GT1b binding
molecular function GO:0004222 metalloendopeptidase activity
molecular function GO:0008320 protein transmembrane transporter activity
molecular function GO:0090729 toxin activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005618 cell wall
cellular component GO:0005576 extracellular region
cellular component GO:0044161 host cell cytoplasmic vesicle
cellular component GO:0044164 host cell cytosol
cellular component GO:0044156 host cell junction
cellular component GO:0044231 host cell presynaptic membrane
cellular component GO:0016021 integral component of membrane
Reactome
Pathway Id Pathway Name
R-HSA-1643685 Disease
R-HSA-168799 Neurotoxicity of clostridium toxins
R-HSA-5250968 Toxicity of botulinum toxin type A (BoNT/A)
R-HSA-5339562 Uptake and actions of bacterial toxins
R-HSA-5663205 Infectious disease
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000116 1,4-Naphtoquinone 158.15
BXGC0000514 2,6-Dimethoxy-1,4-benzoquinone 168.15
BXGC0001403 5-Hydroxy-3,3',4',6,7,8-hexamethoxyflavone 418.39
BXGC0001991 Juglone 174.15
BXGC0003456 1,4-Benzoquinone 108.09
BXGC0004714 2-Methoxy-1,4-benzoquinone 138.12
BXGC0006647 Thymoquinone 164.2
BXGC0007629 Benzaldehyde 106.12
BXGC0016189 Methyl Betulinate 470.38
BXGC0025231 Betunolic Acid 454.34
BXGC0027421 Paclitaxel 853.33
BXGC0031564 Chicoric Acid 474.08
BXGC0035226 Betulinic Acid 456.36
BXGC0042127 Oxyquinoline 145.05
BXGC0044200 Menadione 172.05
BXGC0046518 Chloroquine 319.18
BXGC0049707 Fructose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein