Showing entry for Guanine nucleotide-binding protein G(i) subunit alpha-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007621
Protein NameGuanine nucleotide-binding protein G(i) subunit alpha-1
Uniport IdP10824
GeneGnai1
Gene Id25686
DomainG-alpha
Pfam PF00503  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0007049 cell cycle
Biological Process GO:0051301 cell division
Biological Process GO:1904322 cellular response to forskolin
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0050805 negative regulation of synaptic transmission
Biological Process GO:1904778 positive regulation of protein localization to cell cortex
Biological Process GO:0043949 regulation of cAMP-mediated signaling
Biological Process GO:0060236 regulation of mitotic spindle organization
molecular function GO:0019003 GDP binding
molecular function GO:0031683 G-protein beta/gamma-subunit complex binding
molecular function GO:0001664 G protein-coupled receptor binding
molecular function GO:0031821 G protein-coupled serotonin receptor binding
molecular function GO:0032794 GTPase activating protein binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0000287 magnesium ion binding
cellular component GO:0099738 cell cortex region
cellular component GO:0005813 centrosome
cellular component GO:0005737 cytoplasm
cellular component GO:0005834 heterotrimeric G-protein complex
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0030496 midbody
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0006198 Citric acid 192.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein