Showing entry for Sarcoplasmic/endoplasmic reticulum calcium ATPase 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007728
Protein NameSarcoplasmic/endoplasmic reticulum calcium ATPase 2
Uniport IdP11607
GeneATP2A2
Gene Id396875
DomainCation_ATPase; Cation_ATPase_C; Cation_ATPase_N; E1-E2_ATPase
Pfam PF00689   PF00690  
OrganismSus scrofa (Pig)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum
Biological Process GO:0014898 cardiac muscle hypertrophy in response to stress
Biological Process GO:0006874 cellular calcium ion homeostasis
Biological Process GO:0034599 cellular response to oxidative stress
Biological Process GO:0006984 ER-nucleus signaling pathway
Biological Process GO:0045822 negative regulation of heart contraction
Biological Process GO:1900121 negative regulation of receptor binding
Biological Process GO:0006996 organelle organization
Biological Process GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration
Biological Process GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter
Biological Process GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling
Biological Process GO:0002026 regulation of the force of heart contraction
Biological Process GO:0070296 sarcoplasmic reticulum calcium ion transport
Biological Process GO:0014883 transition between fast and slow fiber
Biological Process GO:0033292 T-tubule organization
molecular function GO:0016887 ATPase activity
molecular function GO:0005524 ATP binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0005388 calcium transmembrane transporter activity, phosphorylative mechanism
molecular function GO:0086039 calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential
molecular function GO:0019899 enzyme binding
molecular function GO:0044325 ion channel binding
molecular function GO:0008553 proton-exporting ATPase activity, phosphorylative mechanism
molecular function GO:0044548 S100 protein binding
cellular component GO:0016021 integral component of membrane
cellular component GO:0097470 ribbon synapse
cellular component GO:0033017 sarcoplasmic reticulum membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0002591 Potassium 39.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein