Showing entry for Ryanodine receptor 1



                       
General Target Information
BXGT IdBXGT007739
Protein NameRyanodine receptor 1
Uniport IdP11716
GeneRYR1
Gene Id100009540
DomainEF-hand_8; Ins145_P3_rec; Ion_trans; MIR; RIH_assoc; RR_TM4-6; RYDR_ITPR; RyR; SPRY
Pfam PF08709   PF00520   PF02815   PF08454   PF06459   PF01365   PF02026   PF00622  
OrganismOryctolagus cuniculus (Rabbit)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0071313 cellular response to caffeine
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0006936 muscle contraction
Biological Process GO:0043931 ossification involved in bone maturation
Biological Process GO:0003151 outflow tract morphogenesis
Biological Process GO:0051289 protein homotetramerization
Biological Process GO:0051209 release of sequestered calcium ion into cytosol
Biological Process GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
Biological Process GO:0048741 skeletal muscle fiber development
Biological Process GO:0043588 skin development
molecular function GO:0005524 ATP binding
molecular function GO:0035381 ATP-gated ion channel activity
molecular function GO:0005262 calcium channel activity
molecular function GO:0005509 calcium ion binding
molecular function GO:0015278 calcium-release channel activity
molecular function GO:0005516 calmodulin binding
molecular function GO:0097718 disordered domain specific binding
molecular function GO:0008144 drug binding
molecular function GO:0042802 identical protein binding
molecular function GO:0044325 ion channel binding
molecular function GO:0005219 ryanodine-sensitive calcium-release channel activity
molecular function GO:0015643 toxic substance binding
molecular function GO:0005245 voltage-gated calcium channel activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0031301 integral component of organelle membrane
cellular component GO:0016020 membrane
cellular component GO:1990425 ryanodine receptor complex
cellular component GO:0016529 sarcoplasmic reticulum
cellular component GO:0033017 sarcoplasmic reticulum membrane
cellular component GO:0014802 terminal cisterna
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002591 Potassium 39.1
BXGC0004266 2-Propanol 60.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein