Showing entry for Gag-Pol polyprotein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007821
Protein NameGag-Pol polyprotein
Uniport IdP12497
Genegag-pol
Gene Id
Domain-
Pfam PF00540   PF00607   PF00552   PF02022   PF00075   PF00665   PF00077   PF00078   PF06815   PF06817   PF00098  
OrganismHuman immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015074 DNA integration
Biological Process GO:0006310 DNA recombination
Biological Process GO:0075713 establishment of integrated proviral latency
Biological Process GO:0039651 induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0039657 suppression by virus of host gene expression
Biological Process GO:0046718 viral entry into host cell
Biological Process GO:0044826 viral genome integration into host DNA
Biological Process GO:0075732 viral penetration into host nucleus
molecular function GO:0004190 aspartic-type endopeptidase activity
molecular function GO:0003677 DNA binding
molecular function GO:0003887 DNA-directed DNA polymerase activity
molecular function GO:0004533 exoribonuclease H activity
molecular function GO:0042802 identical protein binding
molecular function GO:0008289 lipid binding
molecular function GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
molecular function GO:0003723 RNA binding
molecular function GO:0003964 RNA-directed DNA polymerase activity
molecular function GO:0004523 RNA-DNA hybrid ribonuclease activity
molecular function GO:0005198 structural molecule activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0042025 host cell nucleus
cellular component GO:0020002 host cell plasma membrane
cellular component GO:0072494 host multivesicular body
cellular component GO:0019013 viral nucleocapsid
cellular component GO:0055036 virion membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000140 Phytic acid 660.04
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0000559 Indole-beta-carboxylic acid 161.16
BXGC0002144 Tetradecanoic acid 228.37
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0002591 Potassium 39.1
BXGC0002675 Sugars 342.3
BXGC0002692 Arsenic 77.95
BXGC0003705 Chloride 35.45
BXGC0004277 Acetic acid 60.05
BXGC0005753 L-Threonine 119.12
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein