Showing entry for Arachidonate 15-lipoxygenase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007827
Protein NameArachidonate 15-lipoxygenase
Uniport IdP12530
GeneALOX15
Gene Id100009114;100271999
DomainLipoxygenase; PLAT
Pfam PF00305   PF01477  
OrganismOryctolagus cuniculus (Rabbit)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043277 apoptotic cell clearance
Biological Process GO:0019369 arachidonic acid metabolic process
Biological Process GO:0030282 bone mineralization
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0035963 cellular response to interleukin-13
Biological Process GO:0019395 fatty acid oxidation
Biological Process GO:0051122 hepoxilin biosynthetic process
Biological Process GO:0043651 linoleic acid metabolic process
Biological Process GO:0006629 lipid metabolic process
Biological Process GO:2001303 lipoxin A4 biosynthetic process
Biological Process GO:0019372 lipoxygenase pathway
Biological Process GO:0002820 negative regulation of adaptive immune response
Biological Process GO:0001503 ossification
Biological Process GO:0006646 phosphatidylethanolamine biosynthetic process
Biological Process GO:0030838 positive regulation of actin filament polymerization
Biological Process GO:0010811 positive regulation of cell-substrate adhesion
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:1901074 regulation of engulfment of apoptotic cell
Biological Process GO:0050727 regulation of inflammatory response
Biological Process GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway
Biological Process GO:0034976 response to endoplasmic reticulum stress
Biological Process GO:0042060 wound healing
molecular function GO:0004052 arachidonate 12(S)-lipoxygenase activity
molecular function GO:0050473 arachidonate 15-lipoxygenase activity
molecular function GO:0005506 iron ion binding
molecular function GO:0016165 linoleate 13S-lipoxygenase activity
molecular function GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
cellular component GO:0005829 cytosol
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0005811 lipid droplet
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0000202 Papaverine 339.39
BXGC0000204 Theophylline 180.16
BXGC0000226 Glycine 75.07
BXGC0000284 alpha-Tocopherol 430.71
BXGC0000286 L-DOPA 197.19
BXGC0000340 Kaempferol 286.24
BXGC0000433 Triacetin 218.2
BXGC0000434 Ethanol 46.07
BXGC0000439 Chloroform 119.38
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0000528 Salicylic acid 138.12
BXGC0000536 Phenol 94.11
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0000622 Nicotinic acid 123.11
BXGC0000663 Papain 206.28
BXGC0000759 Arabinan 243.22
BXGC0000764 L-Ascorbic acid 176.12
BXGC0000894 2-Methylthioribosyl-trans-zeatin 323.8
BXGC0001000 4,8,5'-Trimethylpsoralen 228.24
BXGC0001002 1,2-Benzenediol 110.11
BXGC0001325 Progesterone 314.46
BXGC0001502 Caffeine 194.19
BXGC0001550 Ficus Latex peptide 2 244.26
BXGC0001767 (E)-Resveratrol 228.25
BXGC0002012 (Z)-Isoeugenol 164.2
BXGC0002402 Ethyl carbamate 89.09
BXGC0002437 Lactic acid 90.08
BXGC0002441 Hydroxyacetic acid 76.05
BXGC0002627 17alpha-ethynylestradiol 296.4
BXGC0002796 Nicotine 162.23
BXGC0002867 Lappaurin 284.74
BXGC0002906 Caffeic acid ester 284.31
BXGC0002916 Melatonin 232.28
BXGC0003066 Phenols 199.27
BXGC0003131 N,N-Dimethylformamide 73.09
BXGC0003281 Isoscopoletin 192.17
BXGC0003501 Parthenolide 248.32
BXGC0003502 Phenylhydrazine 108.14
BXGC0003611 Latex 416.57
BXGC0003690 Glucokinin 764.94
BXGC0003707 Estrogen 268.36
BXGC0003773 Estriol 288.38
BXGC0003956 Fenugrin E 178.19
BXGC0004261 Propylene glycol 76.09
BXGC0004287 Allyl alcohol 58.08
BXGC0004556 1,2,3-Benzenetriol 126.11
BXGC0004560 Benzoic acid 122.12
BXGC0004565 Benzyl alcohol 108.14
BXGC0004587 (E)-3-Phenyl-2-propenal 132.16
BXGC0004712 Methylparaben 152.15
BXGC0005398 (-)-alpha-Narcotine 413.42
BXGC0005508 Safrole 162.19
BXGC0005624 Genistein 270.24
BXGC0005682 3,3',4,4'-Tetrahydroxylignan 302.36
BXGC0005683 Quercetin 302.24
BXGC0005702 2H-1-Benzopyran-2-one 146.15
BXGC0005879 Eugenol 164.2
BXGC0006105 Methyl salicylate 152.15
BXGC0006115 Xanthotoxin 216.19
BXGC0006125 Nicotinamide 122.12
BXGC0006156 Dicoumarol 336.3
BXGC0006198 Citric acid 192.12
BXGC0006291 Scopoletin 192.17
BXGC0006362 Estrone 270.37
BXGC0006366 trans-Ferulic acid 194.18
BXGC0006372 Ergocalciferol 396.65
BXGC0006389 Rotenone 394.42
BXGC0006422 Mercenene 214.05
BXGC0006982 Geraniol 154.25
BXGC0007601 1,8-Cineole 154.25
BXGC0012228 Vitamin D 384.64
BXGC0012243 Ukonan D 151.16
BXGC0013452 Dioctyl phthalate 390.28
BXGC0014443 (-)-Pinoresinol 358.14
BXGC0014695 Loratadine 382.14
BXGC0015594 4-Nonylphenol 220.18
BXGC0015987 L-Mimosine 198.06
BXGC0016470 Camptothecin 348.11
BXGC0016671 Leucovorin 473.17
BXGC0016747 Camphor 152.12
BXGC0016891 Nortriptyline 263.17
BXGC0017115 Cephalexin 347.09
BXGC0017719 Strychnine 334.17
BXGC0018403 Hydroxyprogesterone 330.22
BXGC0018491 Methylprednisolone 374.21
BXGC0018681 (-)-3,3'-Bisdemethylpinoresinol 330.11
BXGC0019117 Tannic Acid 1700.17
BXGC0019164 Raloxifene 473.17
BXGC0020355 Fomepizole 82.05
BXGC0020800 Testosterone 288.21
BXGC0021077 Aconitine 645.31
BXGC0021478 Lipoic Acid 206.04
BXGC0022544 Digoxin 780.43
BXGC0022677 (9Z,11E)-13-Oxooctadeca-9,11-Dienoic Acid 294.22
BXGC0024141 Hydrocortisone 362.21
BXGC0024386 Atractyloside 724.21
BXGC0024413 Emetine 480.3
BXGC0024729 Mercaptopurine 152.02
BXGC0024988 Nifedipine 346.12
BXGC0025658 Vinblastine 810.42
BXGC0026391 Naloxone 327.15
BXGC0026595 Glycyrrhizin 822.4
BXGC0027374 Glyburide 493.14
BXGC0027421 Paclitaxel 853.33
BXGC0027854 Ethosuximide 141.08
BXGC0028885 Secobarbital 238.13
BXGC0030138 Colchicine 399.17
BXGC0030663 Metformin 129.1
BXGC0030685 Physostigmine 275.16
BXGC0031384 Epinephrine 183.09
BXGC0031622 Podofilox 414.13
BXGC0032368 Sparteine 234.21
BXGC0033776 Cycloheximide 281.16
BXGC0034035 Capsaicin 305.2
BXGC0034768 Vincristine 824.4
BXGC0034778 Artemisinin 282.15
BXGC0034783 Doxorubicin 543.17
BXGC0035519 Amygdalin 457.16
BXGC0037718 Ethacrynic Acid 302.01
BXGC0038963 Dichlorvos 219.95
BXGC0039601 Levocarnitine 161.11
BXGC0039684 Berberine Chloride 336.12
BXGC0040042 Warfarin 308.1
BXGC0040462 Aminosalicylic Acid 153.04
BXGC0041240 Atenolol 266.16
BXGC0041503 (+)-3,4,3',4'-Tetrahydroxy-9,7'alpha-Epoxylignano-7 Alpha,9'-Lactone 344.09
BXGC0042127 Oxyquinoline 145.05
BXGC0042179 Atropine 289.17
BXGC0042211 4-Octylphenol 206.17
BXGC0042222 Propranolol 259.16
BXGC0042339 Terbutaline 225.14
BXGC0042452 Panthenol 205.13
BXGC0042510 Fluoxetine 309.13
BXGC0042519 Glimepiride 490.22
BXGC0042596 Isoniazid 137.06
BXGC0043648 (-)-Camphor 152.12
BXGC0044017 Verapamil 454.28
BXGC0044810 Lamivudine 229.05
BXGC0045812 Trifluoperazine 407.16
BXGC0045824 (+)-3,3'-Bisdemethyltanegool 348.12
BXGC0046139 Aminoglutethimide 232.12
BXGC0046755 Yohimbine 354.19
BXGC0046862 Benzo[Def]Chrysene 252.09
BXGC0046996 Thioguanine 167.03
BXGC0047126 Artemether 298.18
BXGC0049391 Betadex 1134.37
BXGC0049738 Dexibuprofen 206.13
BXGC0050471 Fluorouracil 130.02
BXGC0050816 Galantamine 287.15
BXGC0051524 Ouabain 584.28
BXGC0051982 Mannitol 182.08
BXGC0052021 (R)-Ibuprophen 206.13
BXGC0052374 Reserpine 608.27
BXGC0052878 Bisphenol A 228.12
BXGC0053118 Streptomycin 581.27
BXGC0053261 Antimycin A 548.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein