Showing entry for Programmed cell death protein 6


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007848
Protein NameProgrammed cell death protein 6
Uniport IdP12815
GenePdcd6
Gene Id18570
DomainEF-hand_1
Pfam PF13202   PF13499  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0001525 angiogenesis
Biological Process GO:0006915 apoptotic process
Biological Process GO:0034605 cellular response to heat
Biological Process GO:0048208 COPII vesicle coating
Biological Process GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0051898 negative regulation of protein kinase B signaling
Biological Process GO:0032007 negative regulation of TOR signaling
Biological Process GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway
Biological Process GO:0014032 neural crest cell development
Biological Process GO:0014029 neural crest formation
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0010595 positive regulation of endothelial cell migration
Biological Process GO:0001938 positive regulation of endothelial cell proliferation
Biological Process GO:1902527 positive regulation of protein monoubiquitination
Biological Process GO:0051592 response to calcium ion
Biological Process GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway
molecular function GO:0048306 calcium-dependent protein binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0042802 identical protein binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0046983 protein dimerization activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0030674 protein-macromolecule adaptor activity
molecular function GO:0043495 protein-membrane adaptor activity
molecular function GO:1990756 ubiquitin ligase-substrate adaptor activity
cellular component GO:0030127 COPII vesicle coat
cellular component GO:0031463 Cul3-RING ubiquitin ligase complex
cellular component GO:0005737 cytoplasm
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0070971 endoplasmic reticulum exit site
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0005768 endosome
cellular component GO:0000139 Golgi membrane
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0004266 2-Propanol 60.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein