Showing entry for Xaa-Pro dipeptidase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007865
Protein NameXaa-Pro dipeptidase
Uniport IdP12955
GenePEPD
Gene Id5184
DomainAMP_N; Peptidase_M24
Pfam PF05195   PF00557  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006520 cellular amino acid metabolic process
Biological Process GO:0030574 collagen catabolic process
Biological Process GO:0006508 proteolysis
molecular function GO:0030145 manganese ion binding
molecular function GO:0070006 metalloaminopeptidase activity
molecular function GO:0004181 metallocarboxypeptidase activity
molecular function GO:0008233 peptidase activity
molecular function GO:0102009 proline dipeptidase activity
cellular component GO:0070062 extracellular exosome
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001948 BXGD000091 Alcohol consumption Behavior and Behavior Mechanisms
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003706 BXGD000215 Arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0005612 BXGD000317 Birth Weight Pathological Conditions, Signs and Symptoms
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0005890 BXGD000345 Body Height
C0005893 BXGD000346 Body mass index procedure
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007194 BXGD000452 Hypertrophic Cardiomyopathy Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009319 BXGD000596 Colitis Digestive System Diseases
C0011334 BXGD000716 Dental caries Stomatognathic Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014061 BXGD000883 Tick-Borne Encephalitis Infections; Nervous System Diseases
C0014772 BXGD000948 Red Blood Cell Count measurement
C0015300 BXGD000973 Exophthalmos Eye Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0023508 BXGD001675 White Blood Cell Count procedure
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025990 BXGD001884 Micrognathism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0026269 BXGD001897 Mitral Valve Stenosis Cardiovascular Diseases
C0027126 BXGD001976 Myotonic Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0030319 BXGD002208 Panic Disorder Mental Disorders
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0033774 BXGD002419 Pruritus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0037299 BXGD002685 Skin Ulcer Skin and Connective Tissue Diseases
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0040264 BXGD002857 Tinnitus Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0041326 BXGD002915 Pleural Tuberculosis Infections; Respiratory Tract Diseases
C0041834 BXGD002935 Erythema Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0042345 BXGD002977 Varicosity Cardiovascular Diseases
C0042485 BXGD002985 Venous Insufficiency Cardiovascular Diseases
C0151908 BXGD003502 Dry skin Skin and Connective Tissue Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0201973 BXGD004062 Creatine kinase measurement
C0202236 BXGD004086 Triglycerides measurement
C0205682 BXGD004105 Waist-Hip Ratio
C0239998 BXGD005012 Recurrent infections Pathological Conditions, Signs and Symptoms; Infections; Musculoskeletal Diseases
C0240538 BXGD005041 Convex nasal ridge
C0241144 BXGD005080 Petechiae of skin Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0268532 BXGD005974 Deficiency of prolidase Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0332563 BXGD006894 Papule Pathological Conditions, Signs and Symptoms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0344312 BXGD007665 White forelock Skin and Connective Tissue Diseases
C0349506 BXGD007912 Photosensitivity of skin Skin and Connective Tissue Diseases
C0353676 BXGD007957 Organophosphorus Poisoning Chemically-Induced Disorders
C0391976 BXGD008022 Pain Disorder Mental Disorders
C0392885 BXGD008071 High density lipoprotein measurement
C0409959 BXGD008400 Osteoarthritis, Knee Musculoskeletal Diseases
C0423757 BXGD008504 Thin skin
C0424503 BXGD008532 Dysmorphic facies
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0427460 BXGD008616 Red cell distribution width determination
C0518026 BXGD009069 body fat percentage (physical finding)
C0557874 BXGD009444 Global developmental delay
C0576093 BXGD009525 Knee joint valgus deformity Musculoskeletal Diseases
C0578022 BXGD009541 Finding of body mass index
C0581366 BXGD009563 Recurrent cystitis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0694550 BXGD009852 Recurrent pneumonia Infections; Respiratory Tract Diseases
C0700359 BXGD009887 Organophosphate poisoning Chemically-Induced Disorders
C0746102 BXGD010136 Chronic lung disease Respiratory Tract Diseases
C0871470 BXGD011316 Systolic Pressure
C0949658 BXGD011582 Cardiomyopathy, Hypertrophic, Familial Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1265776 BXGD011922 Diffuse telangiectasis Cardiovascular Diseases
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1519353 BXGD013236 Skin Papule Skin and Connective Tissue Diseases
C1519383 BXGD013237 Smoking Behaviors Behavior and Behavior Mechanisms
C1836542 BXGD014129 Depressed nasal bridge
C1837260 BXGD014214 Prominent forehead
C1842366 BXGD014512 Low anterior hairline
C1842876 BXGD014542 Depressed nasal ridge
C1849211 BXGD015023 Generalized hirsutism Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C1854114 BXGD015383 Short nose
C1855728 BXGD015536 Low posterior hairline
C1859236 BXGD015867 Prolonged neonatal jaundice Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1861141 BXGD016014 Abnormality of the middle ear
C1861172 BXGD016016 Venous Thromboembolism Cardiovascular Diseases
C1862095 BXGD016100 Bilateral single transverse palmar creases
C1862475 BXGD016132 Abnormality of retinal pigmentation
C1868496 BXGD016502 Crusting erythematous dermatitis
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1963094 BXGD016681 Dry Skin, CTCAE
C2674432 BXGD017246 Reduced bone mineral density
C2700366 BXGD017465 Adiponectin Measurement
C2937365 BXGD018161 Recurrent aphthous ulcer Stomatognathic Diseases
C3494247 BXGD018959 Organothiophosphonate Poisoning Chemically-Induced Disorders
C3494248 BXGD018960 Organothiophosphate Poisoning Chemically-Induced Disorders
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3714514 BXGD019409 Infection Infections
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3806482 BXGD019514 Recurrent respiratory infections Infections; Respiratory Tract Diseases
C4021242 BXGD020592 Hypoplasia of the zygomatic bone
C4021735 BXGD020743 Abnormality of the hip bone
C4021768 BXGD020766 Abnormality of metabolism/homeostasis
C4049938 BXGD021956 Physical Activity Measurement
C4551675 BXGD023384 Keratoderma, Palmoplantar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000226 Glycine 75.07
BXGC0000288 L-Proline 115.13
BXGC0000436 Glycerol 92.09
BXGC0000942 Phosphoenolpyruvic acid 168.04
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0012311 5-Aminolevulinic acid 131.13
BXGC0032575 Leucine 131.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein