Showing entry for Protein disulfide-isomerase A4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007940
Protein NameProtein disulfide-isomerase A4
Uniport IdP13667
GenePDIA4
Gene Id9601
DomainThioredoxin
Pfam PF00085  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum
5. Organismal Systems 5.2 Endocrine system hsa04918 Thyroid hormone synthesis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05110 Vibrio cholerae infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0045454 cell redox homeostasis
Biological Process GO:0061077 chaperone-mediated protein folding
Biological Process GO:0006457 protein folding
Biological Process GO:0009306 protein secretion
Biological Process GO:0034976 response to endoplasmic reticulum stress
molecular function GO:0015037 peptide disulfide oxidoreductase activity
molecular function GO:0003756 protein disulfide isomerase activity
molecular function GO:0003723 RNA binding
cellular component GO:0009986 cell surface
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005788 endoplasmic reticulum lumen
cellular component GO:0005615 extracellular space
cellular component GO:0042470 melanosome
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2062441 BXGD016897 Influenza A
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein