Showing entry for Annexin A8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007970
Protein NameAnnexin A8
Uniport IdP13928
GeneANXA8
Gene Id653145;728113
DomainAnnexin
Pfam PF00191  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007596 blood coagulation
Biological Process GO:0016197 endosomal transport
Biological Process GO:0007032 endosome organization
Biological Process GO:1900138 negative regulation of phospholipase A2 activity
Biological Process GO:1900004 negative regulation of serine-type endopeptidase activity
molecular function GO:0051015 actin filament binding
molecular function GO:0005544 calcium-dependent phospholipid binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
molecular function GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
molecular function GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
cellular component GO:0062023 collagen-containing extracellular matrix
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0031902 late endosome membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0023418 BXGD001642 leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0085278 BXGD003150 Antiphospholipid Syndrome Immune System Diseases
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0280222 BXGD006723 stage, pancreatic cancer Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2745900 BXGD017568 Promyelocytic leukemia
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein