Showing entry for Sucrase-isomaltase, intestinal


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008009
Protein NameSucrase-isomaltase, intestinal
Uniport IdP14410
GeneSI
Gene Id6476
DomainGlyco_hydro_31; NtCtMGAM_N; Trefoil
Pfam PF01055   PF16863   PF00088  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00052 Galactose metabolism
1. Metabolism 1.1 Carbohydrate metabolism hsa00500 Starch and sucrose metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
5. Organismal Systems 5.4 Digestive system hsa04973 Carbohydrate digestion and absorption
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0005975 carbohydrate metabolic process
Biological Process GO:0044245 polysaccharide digestion
molecular function GO:0030246 carbohydrate binding
molecular function GO:0004574 oligo-1,6-glucosidase activity
molecular function GO:0004575 sucrose alpha-glucosidase activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0005903 brush border
cellular component GO:0070062 extracellular exosome
cellular component GO:0005794 Golgi apparatus
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1643685 Disease
R-HSA-1643685 Disease
R-HSA-189085 Digestion of dietary carbohydrate
R-HSA-5659898 Intestinal saccharidase deficiencies
R-HSA-5659898 Intestinal saccharidase deficiencies
R-HSA-5663084 Diseases of carbohydrate metabolism
R-HSA-5663084 Diseases of carbohydrate metabolism
R-HSA-5668914 Diseases of metabolism
R-HSA-5668914 Diseases of metabolism
R-HSA-8935690 Digestion
R-HSA-8963743 Digestion and absorption
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001125 BXGD000024 Acidosis, Lactic Nutritional and Metabolic Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0002986 BXGD000165 Fabry Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases
C0004763 BXGD000289 Barrett Esophagus Digestive System Diseases; Neoplasms
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007194 BXGD000452 Hypertrophic Cardiomyopathy Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011311 BXGD000714 Dengue Fever Infections
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0017205 BXGD001105 Gaucher Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0017495 BXGD001111 Gerstmann-Straussler-Scheinker Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Infections; Nervous System Diseases
C0017919 BXGD001150 Glycogen Storage Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0017921 BXGD001152 Glycogen storage disease type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0019104 BXGD001285 Hemorrhagic Fevers, Viral Infections
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021655 BXGD001508 Insulin Resistance Nutritional and Metabolic Diseases
C0021831 BXGD001516 Intestinal Diseases Digestive System Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024523 BXGD001781 Malabsorption Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0026850 BXGD001942 Muscular Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027868 BXGD002053 Neuromuscular Diseases Nervous System Diseases
C0028064 BXGD002068 Niemann-Pick Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029438 BXGD002148 Massive Osteolyses Musculoskeletal Diseases
C0030552 BXGD002238 Paresis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0030920 BXGD002263 Peptic Ulcer Digestive System Diseases
C0033375 BXGD002405 Prolactinoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0037822 BXGD002706 Speech Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038187 BXGD002737 Starvation Nutritional and Metabolic Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038644 BXGD002776 Sudden infant death syndrome Pathological Conditions, Signs and Symptoms
C0040822 BXGD002885 Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0085078 BXGD003118 Lysosomal Storage Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0152020 BXGD003519 Gastroparesis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0236734 BXGD004823 Caffeine related disorders
C0259817 BXGD005226 Xerosis Digestive System Diseases; Nervous System Diseases
C0264492 BXGD005395 Chronic respiratory failure Nutritional and Metabolic Diseases; Respiratory Tract Diseases
C0264652 BXGD005408 Hypertensive heart failure Cardiovascular Diseases
C0267971 BXGD005798 Storage disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0271160 BXGD006166 Cortical cataract Eye Diseases
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0282577 BXGD006816 Congenital Disorders of Glycosylation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0334037 BXGD006980 Intestinal metaplasia
C0334108 BXGD006994 Multiple polyps Pathological Conditions, Signs and Symptoms
C0338106 BXGD007167 Adenocarcinoma of colon Digestive System Diseases; Neoplasms
C0342257 BXGD007447 Complications of Diabetes Mellitus Endocrine System Diseases
C0342751 BXGD007542 Generalized glycogen storage disease of infants Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0342753 BXGD007543 Glycogen storage disease due to acid maltase deficiency, late-onset Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0376154 BXGD007980 Skin callus Skin and Connective Tissue Diseases
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0403814 BXGD008313 Congenital bilateral aplasia of vas deferens Male Urogenital Diseases
C0410158 BXGD008408 Muscle damage
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0543515 BXGD009283 Sucrase deficiency
C0545044 BXGD009322 Acrokeratoelastoidosis of Costa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0699848 BXGD009868 Disaccharidase deficiency Digestive System Diseases; Nutritional and Metabolic Diseases
C0741281 BXGD010032 atrial fibrillation new onset
C0751173 BXGD010336 Glycogen Storage Disease Type II, Infantile Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0877008 BXGD011325 Enzyme inhibition disorder
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0917713 BXGD011404 Becker Muscular Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C1145670 BXGD011764 Respiratory Failure Respiratory Tract Diseases
C1258085 BXGD011822 Barrett Epithelium Digestive System Diseases; Neoplasms
C1266044 BXGD011940 Collecting Duct Carcinoma of the Kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1283620 BXGD012165 Sucrase-isomaltase deficiency, congenital Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332460 BXGD012530 Barrett's Adenocarcinoma
C1333762 BXGD012639 Gastric Cardia Adenocarcinoma
C1862103 BXGD016103 Brachydactyly type C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1963165 BXGD016685 Malabsorption, CTCAE
C2609259 BXGD017173 Symphysis Pubis Dysfunction Pathological Conditions, Signs and Symptoms
C2931689 BXGD018049 Dystrophia myotonica 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2960127 BXGD018197 Heart failure with normal ejection fraction Cardiovascular Diseases
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3714745 BXGD019427 Malabsorption Digestive System Diseases
C3888924 BXGD019993 Glycogen storage disease due to acid maltase deficiency, infantile onset Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C4021768 BXGD020766 Abnormality of metabolism/homeostasis
C4023106 BXGD021109 Obstructive azoospermia Male Urogenital Diseases
C4283978 BXGD022427 Primary adenocarcinoma of lower third of esophagus due to Barrett esophagus
C4509226 BXGD022972 Heart failure with preserved ejection fraction [HFpEF]
C4529962 BXGD023178 Fatty Liver Disease
C4551472 BXGD023303 Hypertrophic obstructive cardiomyopathy Cardiovascular Diseases
C4732730 BXGD023895 Blood spots
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000484 2,4,5-Trimethoxybenzaldehyde 196.2
BXGC0003705 Chloride 35.45
BXGC0005683 Quercetin 302.24
BXGC0005793 Baicalein 270.24
BXGC0007559 gamma-Mangostin 396.43
BXGC0007560 alpha-Mangostin 410.46
BXGC0014335 (7R,8S)-dihydrodehydrodiconiferyl alcohol 9-O-beta-D-glucopyranoside 522.21
BXGC0017516 3-(3,4-Dimethoxyphenyl)Propan-1-Ol 196.11
BXGC0018397 beta-1,4-mannan 180.06
BXGC0026407 3,3-Dihydroxyterphenyllin 370.11
BXGC0029684 Cochinchinone A 448.22
BXGC0030304 4,4'-((1S,3Ar,4S,6Ar)-Hexahydrofuro[3,4-C]Furan-1,4-Diyl)Bis(2-Methoxyphenol) 358.14
BXGC0032319 L-Ido-1-Deoxynojirimycin 163.08
BXGC0033407 4''-Deoxyterphenyllin 322.12
BXGC0036329 3-Hydroxyterphenyllin 354.11
BXGC0039586 Prenylterphenyllin 406.18
BXGC0041132 Duvoglustat 163.08
BXGC0043172 1,3,7-Trihydroxy-2,4-Diisoprenylxanthone 380.16
BXGC0043587 Scopolamine 303.15
BXGC0044518 7-Geranyloxy-1,3-dihydroxyxanthone 380.16
BXGC0047088 Ursolic Acid 456.36
BXGC0050194 alpha-D-Mannose 180.06
BXGC0052593 Terphenyllin 338.12
BXGC0052755 Mitorubrinol 398.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein