Showing entry for Small nuclear ribonucleoprotein-associated proteins B and B'


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008038
Protein NameSmall nuclear ribonucleoprotein-associated proteins B and B'
Uniport IdP14678
GeneSNRPB
Gene Id6628
DomainLSM
Pfam PF01423  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.1 Transcription hsa03040 Spliceosome
6. Human Diseases 6.3 Immune diseases hsa05322 Systemic lupus erythematosus
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008334 histone mRNA metabolic process
Biological Process GO:0051170 import into nucleus
Biological Process GO:0000398 mRNA splicing, via spliceosome
Biological Process GO:0006479 protein methylation
Biological Process GO:0008380 RNA splicing
Biological Process GO:0000387 spliceosomal snRNP assembly
Biological Process GO:0006369 termination of RNA polymerase II transcription
molecular function GO:0003723 RNA binding
molecular function GO:0070034 telomerase RNA binding
cellular component GO:0071013 catalytic step 2 spliceosome
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0034709 methylosome
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0030532 small nuclear ribonucleoprotein complex
cellular component GO:0034719 SMN-Sm protein complex
cellular component GO:0005681 spliceosomal complex
cellular component GO:0005697 telomerase holoenzyme complex
cellular component GO:0005689 U12-type spliceosomal complex
cellular component GO:0005685 U1 snRNP
cellular component GO:0005686 U2 snRNP
cellular component GO:0071007 U2-type catalytic step 2 spliceosome
cellular component GO:0071005 U2-type precatalytic spliceosome
cellular component GO:0071004 U2-type prespliceosome
cellular component GO:0046540 U4/U6 x U5 tri-snRNP complex
cellular component GO:0005687 U4 snRNP
cellular component GO:0005682 U5 snRNP
cellular component GO:0005683 U7 snRNP
Reactome
Pathway Id Pathway Name
R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs
R-HSA-191859 snRNP Assembly
R-HSA-194441 Metabolism of non-coding RNA
R-HSA-72163 mRNA Splicing - Major Pathway
R-HSA-72165 mRNA Splicing - Minor Pathway
R-HSA-72172 mRNA Splicing
R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA
R-HSA-73856 RNA Polymerase II Transcription Termination
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-75067 Processing of Capped Intronless Pre-mRNA
R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0008925 BXGD000575 Cleft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0013274 BXGD000809 Patent ductus arteriosus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017668 BXGD001143 Focal glomerulosclerosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018777 BXGD001217 Conductive hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018817 BXGD001235 Atrial Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0018818 BXGD001236 Ventricular Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0020224 BXGD001366 Polyhydramnios Female Urogenital Diseases and Pregnancy Complications
C0020225 BXGD001367 Hydranencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0022821 BXGD001590 Kyphosis deformity of spine Musculoskeletal Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025312 BXGD001861 Meningomyelocele Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0025990 BXGD001884 Micrognathism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0035220 BXGD002512 Respiratory Distress Syndrome, Newborn Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0151860 BXGD003490 Acquired porencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0221217 BXGD004408 Neck webbing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0221353 BXGD004445 Horseshoe Kidney Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0231528 BXGD004496 Myalgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0232466 BXGD004543 Feeding difficulties
C0235874 BXGD004781 Disease Exacerbation Pathological Conditions, Signs and Symptoms
C0238207 BXGD004894 Ectopic kidney Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0239234 BXGD004974 Low set ears
C0240635 BXGD005047 Byzanthine arch palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Stomatognathic Diseases
C0262444 BXGD005244 Abnormality of the dentition Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0265245 BXGD005479 Nager syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases
C0265342 BXGD005525 Cerebrocostomandibular Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Stomatognathic Diseases; Behavior and Behavior Mechanisms
C0267048 BXGD005728 Glossoptosis Stomatognathic Diseases
C0268800 BXGD006041 Simple renal cyst Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0270685 BXGD006084 Cerebral calcification Nutritional and Metabolic Diseases; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0349588 BXGD007933 Short stature
C0409338 BXGD008381 Flexion contracture - elbow
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0426827 BXGD008589 Gap in ribs
C0431478 BXGD008692 Posteriorly rotated ear
C0432098 BXGD008721 Cleft Soft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0566620 BXGD009490 Nasal voice
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678230 BXGD009750 Congenital Epicanthus
C0948187 BXGD011513 Tracheomalacia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Respiratory Tract Diseases
C1285162 BXGD012167 Degenerative disorder Pathological Conditions, Signs and Symptoms
C1285498 BXGD012171 Vegetation
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332140 BXGD012489 Acrofacial Dysostosis Musculoskeletal Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1708349 BXGD013597 Hereditary Diffuse Gastric Cancer Digestive System Diseases; Neoplasms
C1832117 BXGD013798 Short humerus
C1837482 BXGD014237 Thoracic hypoplasia
C1839731 BXGD014397 11 pairs of ribs
C1842696 BXGD014533 Posterior rib gap
C1850049 BXGD015101 Clinodactyly of the 5th finger
C1858085 BXGD015770 Malar flattening
C1858430 BXGD015792 Death in infancy
C1859308 BXGD015871 PREMATURE CENTROMERE DIVISION
C1859778 BXGD015931 Postnatal growth retardation
C1861704 BXGD016067 Anomalous rib insertion to vertebrae
C1861708 BXGD016068 Calcaneal epiphyseal stippling
C1863406 BXGD016176 Anomalous tracheal cartilage
C1865014 BXGD016282 Long philtrum
C1865186 BXGD016296 Bell-shaped thorax
C1866190 BXGD016384 Atresia of the external auditory canal
C2919142 BXGD017867 Short Stature, CTCAE
C3489532 BXGD018934 Cone-Rod Dystrophy 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C3501912 BXGD019034 Cerebrocostomandibular-Like Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Stomatognathic Diseases; Behavior and Behavior Mechanisms
C3714581 BXGD019415 Multicystic Dysplastic Kidney Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3887499 BXGD019884 Renal cyst Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4023918 BXGD021277 Short hard palate
C4082172 BXGD022086 Porencephalic cyst
C4085590 BXGD022119 Cone-Rod Dystrophies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C4281993 BXGD022418 Neonatal respiratory distress Respiratory Tract Diseases
C4551649 BXGD023382 Congenital Dysplasia Of The Hip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C4551720 BXGD023400 Primary Ciliary Dyskinesia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002591 Potassium 39.1
BXGC0006198 Citric acid 192.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein