Showing entry for Androgen receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008096
Protein NameAndrogen receptor
Uniport IdP15207
GeneAr
Gene Id24208
DomainAndrogen_recep; Hormone_recep; zf-C4
Pfam PF02166   PF00104   PF00105  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0060520 activation of prostate induction by androgen receptor signaling pathway
Biological Process GO:0030521 androgen receptor signaling pathway
Biological Process GO:0048645 animal organ formation
Biological Process GO:0009987 cellular process
Biological Process GO:0071372 cellular response to follicle-stimulating hormone stimulus
Biological Process GO:0071383 cellular response to steroid hormone stimulus
Biological Process GO:0071394 cellular response to testosterone stimulus
Biological Process GO:0007620 copulation
Biological Process GO:0060742 epithelial cell differentiation involved in prostate gland development
Biological Process GO:0003382 epithelial cell morphogenesis
Biological Process GO:0009566 fertilization
Biological Process GO:0030522 intracellular receptor signaling pathway
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis
Biological Process GO:0033327 Leydig cell differentiation
Biological Process GO:0008049 male courtship behavior
Biological Process GO:0048808 male genitalia morphogenesis
Biological Process GO:0008584 male gonad development
Biological Process GO:0046661 male sex differentiation
Biological Process GO:0019102 male somatic sex determination
Biological Process GO:0060749 mammary gland alveolus development
Biological Process GO:0060571 morphogenesis of an epithelial fold
Biological Process GO:0035264 multicellular organism growth
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0050680 negative regulation of epithelial cell proliferation
Biological Process GO:2001237 negative regulation of extrinsic apoptotic signaling pathway
Biological Process GO:0045720 negative regulation of integrin biosynthetic process
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0045597 positive regulation of cell differentiation
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway
Biological Process GO:0045726 positive regulation of integrin biosynthetic process
Biological Process GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:0060406 positive regulation of penile erection
Biological Process GO:0042327 positive regulation of phosphorylation
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0045945 positive regulation of transcription by RNA polymerase III
Biological Process GO:0060740 prostate gland epithelium morphogenesis
Biological Process GO:0060736 prostate gland growth
Biological Process GO:0048638 regulation of developmental growth
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0060685 regulation of prostatic bud formation
Biological Process GO:1903076 regulation of protein localization to plasma membrane
Biological Process GO:0003073 regulation of systemic arterial blood pressure
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0019098 reproductive behavior
Biological Process GO:0048608 reproductive structure development
Biological Process GO:0061458 reproductive system development
Biological Process GO:0032355 response to estradiol
Biological Process GO:0032868 response to insulin
Biological Process GO:0033574 response to testosterone
Biological Process GO:0072520 seminiferous tubule development
Biological Process GO:0007338 single fertilization
Biological Process GO:0014734 skeletal muscle hypertrophy
Biological Process GO:0007283 spermatogenesis
Biological Process GO:0060748 tertiary branching involved in mammary gland duct morphogenesis
Biological Process GO:0006351 transcription, DNA-templated
molecular function GO:0005497 androgen binding
molecular function GO:0050681 androgen receptor binding
molecular function GO:0051117 ATPase binding
molecular function GO:0008013 beta-catenin binding
molecular function GO:0003682 chromatin binding
molecular function GO:0003677 DNA binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0019899 enzyme binding
molecular function GO:0004879 nuclear receptor activity
molecular function GO:0070974 POU domain binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0070491 repressing transcription factor binding
molecular function GO:0032553 ribonucleotide binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0001091 RNA polymerase II general transcription initiation factor binding
molecular function GO:0001085 RNA polymerase II transcription factor binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:0005102 signaling receptor binding
molecular function GO:0005496 steroid binding
molecular function GO:0008134 transcription factor binding
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0030424 axon
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0000790 nuclear chromatin
cellular component GO:0016607 nuclear speck
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0000202 Papaverine 339.39
BXGC0000204 Theophylline 180.16
BXGC0000226 Glycine 75.07
BXGC0000284 alpha-Tocopherol 430.71
BXGC0000286 L-DOPA 197.19
BXGC0000433 Triacetin 218.2
BXGC0000434 Ethanol 46.07
BXGC0000439 Chloroform 119.38
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0000497 Vanillin 152.15
BXGC0000528 Salicylic acid 138.12
BXGC0000536 Phenol 94.11
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0000622 Nicotinic acid 123.11
BXGC0000663 Papain 206.28
BXGC0000759 Arabinan 243.22
BXGC0000764 L-Ascorbic acid 176.12
BXGC0000894 2-Methylthioribosyl-trans-zeatin 323.8
BXGC0001000 4,8,5'-Trimethylpsoralen 228.24
BXGC0001002 1,2-Benzenediol 110.11
BXGC0001325 Progesterone 314.46
BXGC0001502 Caffeine 194.19
BXGC0001550 Ficus Latex peptide 2 244.26
BXGC0001767 (E)-Resveratrol 228.25
BXGC0002012 (Z)-Isoeugenol 164.2
BXGC0002402 Ethyl carbamate 89.09
BXGC0002437 Lactic acid 90.08
BXGC0002441 Hydroxyacetic acid 76.05
BXGC0002627 17alpha-ethynylestradiol 296.4
BXGC0002781 Flavonoids 224.25
BXGC0002796 Nicotine 162.23
BXGC0002867 Lappaurin 284.74
BXGC0002906 Caffeic acid ester 284.31
BXGC0002916 Melatonin 232.28
BXGC0003066 Phenols 199.27
BXGC0003131 N,N-Dimethylformamide 73.09
BXGC0003501 Parthenolide 248.32
BXGC0003502 Phenylhydrazine 108.14
BXGC0003611 Latex 416.57
BXGC0003690 Glucokinin 764.94
BXGC0003707 Estrogen 268.36
BXGC0003773 Estriol 288.38
BXGC0003776 Flavones 222.24
BXGC0003956 Fenugrin E 178.19
BXGC0004261 Propylene glycol 76.09
BXGC0004287 Allyl alcohol 58.08
BXGC0004556 1,2,3-Benzenetriol 126.11
BXGC0004560 Benzoic acid 122.12
BXGC0004565 Benzyl alcohol 108.14
BXGC0004569 Benzophenone 182.22
BXGC0004577 4-tert-Butylphenol 150.22
BXGC0004587 (E)-3-Phenyl-2-propenal 132.16
BXGC0004712 Methylparaben 152.15
BXGC0005398 (-)-alpha-Narcotine 413.42
BXGC0005442 Testosterone 288.42
BXGC0005502 Coumestrol 268.22
BXGC0005508 Safrole 162.19
BXGC0005624 Genistein 270.24
BXGC0005702 2H-1-Benzopyran-2-one 146.15
BXGC0005879 Eugenol 164.2
BXGC0006105 Methyl salicylate 152.15
BXGC0006115 Xanthotoxin 216.19
BXGC0006125 Nicotinamide 122.12
BXGC0006156 Dicoumarol 336.3
BXGC0006198 Citric acid 192.12
BXGC0006362 Estrone 270.37
BXGC0006366 trans-Ferulic acid 194.18
BXGC0006372 Ergocalciferol 396.65
BXGC0006389 Rotenone 394.42
BXGC0006422 Mercenene 214.05
BXGC0006982 Geraniol 154.25
BXGC0007601 1,8-Cineole 154.25
BXGC0012228 Vitamin D 384.64
BXGC0012243 Ukonan D 151.16
BXGC0013452 Dioctyl phthalate 390.28
BXGC0014695 Loratadine 382.14
BXGC0015594 4-Nonylphenol 220.18
BXGC0015987 L-Mimosine 198.06
BXGC0016470 Camptothecin 348.11
BXGC0016671 Leucovorin 473.17
BXGC0016698 Triptophenolide 312.17
BXGC0016747 Camphor 152.12
BXGC0016891 Nortriptyline 263.17
BXGC0017115 Cephalexin 347.09
BXGC0017719 Strychnine 334.17
BXGC0017757 Androstenedione 286.19
BXGC0018403 Hydroxyprogesterone 330.22
BXGC0018491 Methylprednisolone 374.21
BXGC0019117 Tannic Acid 1700.17
BXGC0019164 Raloxifene 473.17
BXGC0019293 Norethynodrel 298.19
BXGC0020355 Fomepizole 82.05
BXGC0020800 Testosterone 288.21
BXGC0021077 Aconitine 645.31
BXGC0021478 Lipoic Acid 206.04
BXGC0022544 Digoxin 780.43
BXGC0024141 Hydrocortisone 362.21
BXGC0024386 Atractyloside 724.21
BXGC0024413 Emetine 480.3
BXGC0024729 Mercaptopurine 152.02
BXGC0024988 Nifedipine 346.12
BXGC0025658 Vinblastine 810.42
BXGC0026391 Naloxone 327.15
BXGC0026595 Glycyrrhizin 822.4
BXGC0027374 Glyburide 493.14
BXGC0027421 Paclitaxel 853.33
BXGC0027854 Ethosuximide 141.08
BXGC0028885 Secobarbital 238.13
BXGC0029355 Pregnenolone 316.24
BXGC0029905 4-(2-Phenylpropan-2-Yl)Phenol 212.12
BXGC0030138 Colchicine 399.17
BXGC0030663 Metformin 129.1
BXGC0030685 Physostigmine 275.16
BXGC0031384 Epinephrine 183.09
BXGC0031622 Podofilox 414.13
BXGC0032368 Sparteine 234.21
BXGC0033776 Cycloheximide 281.16
BXGC0034035 Capsaicin 305.2
BXGC0034768 Vincristine 824.4
BXGC0034778 Artemisinin 282.15
BXGC0034783 Doxorubicin 543.17
BXGC0035519 Amygdalin 457.16
BXGC0036458 4-(2-Methylbutan-2-Yl)Phenol 164.12
BXGC0037718 Ethacrynic Acid 302.01
BXGC0038316 Cholesterol 386.35
BXGC0038963 Dichlorvos 219.95
BXGC0039601 Levocarnitine 161.11
BXGC0039684 Berberine Chloride 336.12
BXGC0040042 Warfarin 308.1
BXGC0040462 Aminosalicylic Acid 153.04
BXGC0040871 4-sec-Butylphenol 150.1
BXGC0041240 Atenolol 266.16
BXGC0042127 Oxyquinoline 145.05
BXGC0042179 Atropine 289.17
BXGC0042211 4-Octylphenol 206.17
BXGC0042222 Propranolol 259.16
BXGC0042339 Terbutaline 225.14
BXGC0042349 17-Deoxoestrone 256.18
BXGC0042452 Panthenol 205.13
BXGC0042510 Fluoxetine 309.13
BXGC0042519 Glimepiride 490.22
BXGC0042596 Isoniazid 137.06
BXGC0042708 3-Chlorophenol 128
BXGC0043648 (-)-Camphor 152.12
BXGC0044017 Verapamil 454.28
BXGC0044810 Lamivudine 229.05
BXGC0045812 Trifluoperazine 407.16
BXGC0046139 Aminoglutethimide 232.12
BXGC0046755 Yohimbine 354.19
BXGC0046862 Benzo[Def]Chrysene 252.09
BXGC0046996 Thioguanine 167.03
BXGC0047126 Artemether 298.18
BXGC0047871 7-Hydroxyflavone 238.06
BXGC0049391 Betadex 1134.37
BXGC0049738 Dexibuprofen 206.13
BXGC0049858 Chalcone 208.09
BXGC0050471 Fluorouracil 130.02
BXGC0050816 Galantamine 287.15
BXGC0051524 Ouabain 584.28
BXGC0051982 Mannitol 182.08
BXGC0052021 (R)-Ibuprophen 206.13
BXGC0052374 Reserpine 608.27
BXGC0052878 Bisphenol A 228.12
BXGC0053114 Propylparaben 180.08
BXGC0053118 Streptomycin 581.27
BXGC0053261 Antimycin A 548.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein