Showing entry for Voltage-dependent L-type calcium channel subunit alpha-1C


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008115
Protein NameVoltage-dependent L-type calcium channel subunit alpha-1C
Uniport IdP15381
GeneCACNA1C
Gene Id100101555
DomainCAC1F_C; Ca_chan_IQ; GPHH; Ion_trans
Pfam PF08763   PF16885   PF16905   PF00520  
OrganismOryctolagus cuniculus (Rabbit)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel
Biological Process GO:0060402 calcium ion transport into cytosol
Biological Process GO:0061337 cardiac conduction
Biological Process GO:0045762 positive regulation of adenylate cyclase activity
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
Biological Process GO:0098903 regulation of membrane repolarization during action potential
molecular function GO:0005516 calmodulin binding
molecular function GO:0008331 high voltage-gated calcium channel activity
molecular function GO:0046872 metal ion binding
molecular function GO:0005245 voltage-gated calcium channel activity
cellular component GO:0030425 dendrite
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:1990454 L-type voltage-gated calcium channel complex
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0098839 postsynaptic density membrane
cellular component GO:0042383 sarcolemma
cellular component GO:0030315 T-tubule
cellular component GO:0005891 voltage-gated calcium channel complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0007525 (-)-Menthol 156.27
BXGC0024988 Nifedipine 346.12
BXGC0044017 Verapamil 454.28
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein