Showing entry for Sodium channel protein type 5 subunit alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008118
Protein NameSodium channel protein type 5 subunit alpha
Uniport IdP15389
GeneScn5a
Gene Id25665
DomainIon_trans; Na_trans_assoc; Na_trans_cytopl
Pfam PF00520   PF06512   PF11933  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0086014 atrial cardiac muscle cell action potential
Biological Process GO:0086016 AV node cell action potential
Biological Process GO:0086067 AV node cell to bundle of His cell communication
Biological Process GO:0003360 brainstem development
Biological Process GO:0086043 bundle of His cell action potential
Biological Process GO:0055074 calcium ion homeostasis
Biological Process GO:0086002 cardiac muscle cell action potential involved in contraction
Biological Process GO:0060048 cardiac muscle contraction
Biological Process GO:0003231 cardiac ventricle development
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0021549 cerebellum development
Biological Process GO:0051899 membrane depolarization
Biological Process GO:0086010 membrane depolarization during action potential
Biological Process GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential
Biological Process GO:0086045 membrane depolarization during AV node cell action potential
Biological Process GO:0086048 membrane depolarization during bundle of His cell action potential
Biological Process GO:0086012 membrane depolarization during cardiac muscle cell action potential
Biological Process GO:0086047 membrane depolarization during Purkinje myocyte cell action potential
Biological Process GO:0086046 membrane depolarization during SA node cell action potential
Biological Process GO:0019228 neuronal action potential
Biological Process GO:0042475 odontogenesis of dentin-containing tooth
Biological Process GO:0045760 positive regulation of action potential
Biological Process GO:0050679 positive regulation of epithelial cell proliferation
Biological Process GO:0010460 positive regulation of heart rate
Biological Process GO:0010765 positive regulation of sodium ion transport
Biological Process GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization
Biological Process GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization
Biological Process GO:0086004 regulation of cardiac muscle cell contraction
Biological Process GO:0002027 regulation of heart rate
Biological Process GO:0086091 regulation of heart rate by cardiac conduction
Biological Process GO:1902305 regulation of sodium ion transmembrane transport
Biological Process GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization
Biological Process GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization
Biological Process GO:0014894 response to denervation involved in regulation of muscle adaptation
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0086015 SA node cell action potential
Biological Process GO:0035725 sodium ion transmembrane transport
Biological Process GO:0006814 sodium ion transport
Biological Process GO:0021537 telencephalon development
Biological Process GO:0086005 ventricular cardiac muscle cell action potential
molecular function GO:0030506 ankyrin binding
molecular function GO:0005516 calmodulin binding
molecular function GO:0005261 cation channel activity
molecular function GO:0019899 enzyme binding
molecular function GO:0017134 fibroblast growth factor binding
molecular function GO:0044325 ion channel binding
molecular function GO:0050998 nitric-oxide synthase binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0097110 scaffold protein binding
molecular function GO:0031625 ubiquitin protein ligase binding
molecular function GO:0005244 voltage-gated ion channel activity
molecular function GO:0005248 voltage-gated sodium channel activity
molecular function GO:0086060 voltage-gated sodium channel activity involved in AV node cell action potential
molecular function GO:0086061 voltage-gated sodium channel activity involved in bundle of His cell action potential
molecular function GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential
molecular function GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential
molecular function GO:0086063 voltage-gated sodium channel activity involved in SA node cell action potential
cellular component GO:0005901 caveola
cellular component GO:0009986 cell surface
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0016021 integral component of membrane
cellular component GO:0014704 intercalated disc
cellular component GO:0016328 lateral plasma membrane
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0042383 sarcolemma
cellular component GO:0034706 sodium channel complex
cellular component GO:0030315 T-tubule
cellular component GO:0001518 voltage-gated sodium channel complex
cellular component GO:0030018 Z disc
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0035201 Quinidine 324.18
BXGC0049369 Tetrodotoxin 319.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein