Showing entry for NADPH--cytochrome P450 reductase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008226
Protein NameNADPH--cytochrome P450 reductase
Uniport IdP16435
GenePOR
Gene Id5447
DomainFAD_binding_1; Flavodoxin_1; NAD_binding_1
Pfam PF00667   PF00258   PF00175  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009437 carnitine metabolic process
Biological Process GO:0090346 cellular organofluorine metabolic process
Biological Process GO:0071372 cellular response to follicle-stimulating hormone stimulus
Biological Process GO:0071375 cellular response to peptide hormone stimulus
Biological Process GO:0070988 demethylation
Biological Process GO:0019395 fatty acid oxidation
Biological Process GO:0009812 flavonoid metabolic process
Biological Process GO:0018393 internal peptidyl-lysine acetylation
Biological Process GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0060192 negative regulation of lipase activity
Biological Process GO:0043602 nitrate catabolic process
Biological Process GO:0046210 nitric oxide catabolic process
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0045542 positive regulation of cholesterol biosynthetic process
Biological Process GO:0032332 positive regulation of chondrocyte differentiation
Biological Process GO:0032770 positive regulation of monooxygenase activity
Biological Process GO:0045880 positive regulation of smoothened signaling pathway
Biological Process GO:0090031 positive regulation of steroid hormone biosynthetic process
Biological Process GO:0003420 regulation of growth plate cartilage chondrocyte proliferation
Biological Process GO:0042493 response to drug
Biological Process GO:0009725 response to hormone
Biological Process GO:0007584 response to nutrient
Biological Process GO:0006805 xenobiotic metabolic process
molecular function GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H
molecular function GO:0009055 electron transfer activity
molecular function GO:0019899 enzyme binding
molecular function GO:0050660 flavin adenine dinucleotide binding
molecular function GO:0010181 FMN binding
molecular function GO:0016787 hydrolase activity
molecular function GO:0047726 iron-cytochrome-c reductase activity
molecular function GO:0050661 NADP binding
molecular function GO:0003958 NADPH-hemoprotein reductase activity
molecular function GO:0008941 nitric oxide dioxygenase activity
molecular function GO:0016491 oxidoreductase activity
molecular function GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
cellular component GO:0005829 cytosol
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-211859 Biological oxidations
R-HSA-211897 Cytochrome P450 - arranged by substrate type
R-HSA-211945 Phase I - Functionalization of compounds
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0001627 BXGD000068 Congenital adrenal hyperplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002453 BXGD000117 Amenorrhea Pathological Conditions, Signs and Symptoms
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0003706 BXGD000215 Arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0003803 BXGD000220 Arnold Chiari Malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007621 BXGD000468 Neoplastic Cell Transformation Pathological Conditions, Signs and Symptoms; Neoplasms
C0008297 BXGD000522 Choanal Atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0008495 BXGD000548 Chorioamnionitis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0009363 BXGD000599 Congenital ocular coloboma (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0010481 BXGD000673 Cushing Syndrome Endocrine System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015300 BXGD000973 Exophthalmos Eye Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017638 BXGD001132 Glioma Neoplasms
C0017654 BXGD001136 Glomerular Filtration Rate
C0018777 BXGD001217 Conductive hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018817 BXGD001235 Atrial Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0019572 BXGD001338 Hirsutism Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0019911 BXGD001352 Hookworm Infections Infections
C0020255 BXGD001369 Hydrocephalus Nervous System Diseases
C0020433 BXGD001379 Hyperbilirubinemia Pathological Conditions, Signs and Symptoms
C0020445 BXGD001386 Hypercholesterolemia, Familial Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0020649 BXGD001459 Hypotension Cardiovascular Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023186 BXGD001613 Learning Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024809 BXGD001808 Marijuana Abuse Chemically-Induced Disorders; Mental Disorders
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0032796 BXGD002372 Postpartum Amenorrhea Pathological Conditions, Signs and Symptoms
C0034012 BXGD002449 Delayed Puberty Endocrine System Diseases
C0034734 BXGD002486 Raynaud Disease Cardiovascular Diseases
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0039093 BXGD002789 Congenital abnormal Synostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0039128 BXGD002794 Syphilis Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0042510 BXGD002987 Ventricular Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0042514 BXGD002989 Tachycardia, Ventricular Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0042582 BXGD002993 Vesicovaginal Fistula Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0079924 BXGD003103 Oligohydramnios Female Urogenital Diseases and Pregnancy Complications
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0151639 BXGD003452 Decreased fertility in females Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0151640 BXGD003453 Decreased fertility in males Male Urogenital Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0156394 BXGD003856 Hypertrophy of clitoris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0158113 BXGD003875 Contracture of joint of hand Musculoskeletal Diseases
C0158761 BXGD003905 Radioulnar Synostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0200638 BXGD004043 Eosinophil count procedure
C0206624 BXGD004190 Hepatoblastoma Neoplasms
C0206667 BXGD004228 Adrenal Cortical Adenoma Neoplasms; Endocrine System Diseases
C0206726 BXGD004271 gliosarcoma Neoplasms
C0220724 BXGD004332 CONSTRICTING BANDS, CONGENITAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0221182 BXGD004401 Chordee Male Urogenital Diseases
C0221353 BXGD004445 Horseshoe Kidney Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0221354 BXGD004446 Frontal bossing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221356 BXGD004448 Brachycephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221369 BXGD004453 Acquired Camptodactyly
C0234253 BXGD004647 Rest pain Pathological Conditions, Signs and Symptoms
C0235991 BXGD004802 Small for gestational age (disorder) Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0236734 BXGD004823 Caffeine related disorders
C0238395 BXGD004922 Male Pseudohermaphroditism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0239234 BXGD004974 Low set ears
C0240912 BXGD005062 Vertical Talus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0241011 BXGD005073 Low serum estradiol levels
C0241240 BXGD005089 Tall stature
C0241355 BXGD005092 Small testicle
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262405 BXGD005237 Cerebral dysfunction Nervous System Diseases
C0264303 BXGD005379 Laryngomalacia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0264353 BXGD005382 Bronchomalacia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Respiratory Tract Diseases
C0264490 BXGD005394 Acute respiratory failure Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Respiratory Tract Diseases
C0265610 BXGD005555 Clinodactyly of fingers Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0265654 BXGD005559 Tarsal Coalition Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0265677 BXGD005564 Congenital hemivertebra Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0266275 BXGD005641 Ectopic adrenal gland Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0266362 BXGD005657 Ambiguous Genitalia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0302280 BXGD006836 Adrenogenital Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0302511 BXGD006849 Small for gestational age fetus Pathological Conditions, Signs and Symptoms
C0333068 BXGD006920 Flexion contracture Musculoskeletal Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0338908 BXGD007218 Mixed anxiety and depressive disorder Mental Disorders
C0341787 BXGD007422 Bifid scrotum
C0342443 BXGD007481 Adrenal Cushing's syndrome Endocrine System Diseases
C0342527 BXGD007496 Deficiency of testosterone biosynthesis Endocrine System Diseases
C0342546 BXGD007502 Premature adrenarche
C0345309 BXGD007725 Hypoplasia of vagina Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0345958 BXGD007751 Large cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0349588 BXGD007933 Short stature
C0395837 BXGD008169 Stenosis of external auditory canal
C0404572 BXGD008322 Female infertility associated with anovulation Female Urogenital Diseases and Pregnancy Complications
C0426790 BXGD008577 Narrow thorax
C0431659 BXGD008699 Hypoplasia of scrotum
C0431863 BXGD008709 Carpal synostosis
C0452148 BXGD008833 Hypospadias, perineal Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0520463 BXGD009085 Chronic active hepatitis Digestive System Diseases
C0520904 BXGD009121 Postoperative Nausea Pathological Conditions, Signs and Symptoms
C0541764 BXGD009259 Delayed bone age
C0545053 BXGD009323 Advanced bone age
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0566899 BXGD009494 Small labia majora
C0584837 BXGD009578 Choanal stenosis Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0584960 BXGD009579 Factor V Leiden mutation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0596887 BXGD009648 mathematical ability
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0685409 BXGD009810 Congenital Camptodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0702166 BXGD009912 Acne Skin and Connective Tissue Diseases
C0740852 BXGD010011 Upper airway obstruction
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0745103 BXGD010114 Hyperlipoproteinemia Type IIa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0751262 BXGD010368 Adult Learning Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0751263 BXGD010369 Learning Disturbance Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0751265 BXGD010370 Learning Disabilities Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0751772 BXGD010583 REM Sleep Behavior Disorder Nervous System Diseases; Mental Disorders
C0810330 BXGD010845 preeclampsia and eclampsia
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0852654 BXGD010947 21-hydroxylase deficiency
C0857379 BXGD011148 Abnormality of the pinna
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C0948379 BXGD011533 Impaired insulin secretion
C1112442 BXGD011668 Female sexual dysfunction
C1145670 BXGD011764 Respiratory Failure Respiratory Tract Diseases
C1280777 BXGD012128 displaced uterus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1291312 BXGD012208 Deficiency of oxidase
C1291557 BXGD012217 Deficiency of lyase
C1298820 BXGD012252 Aneurysm of aortic root Cardiovascular Diseases
C1304508 BXGD012341 Spindle cell hemangioma Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1321884 BXGD012448 Atresia of vagina
C1330966 BXGD012478 Developmental Academic Disorder Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C1333977 BXGD012663 Hepatitis B Virus-Related Hepatocellular Carcinoma
C1384670 BXGD012949 Single umbilical artery Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1387005 BXGD012953 Penis agenesis Male Urogenital Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1504532 BXGD013149 Post transplant diabetes mellitus
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1833340 BXGD013918 Synostotic Posterior Plagiocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1836542 BXGD014129 Depressed nasal bridge
C1836623 BXGD014139 Decreased circulating cortisol level Immune System Diseases; Endocrine System Diseases
C1837532 BXGD014246 Fused labia minora
C1848103 BXGD014905 Narrow pelvis bone
C1848178 BXGD014909 Female external genitalia in individual with 46,XY karyotype
C1850325 BXGD015128 Labial hypoplasia
C1853242 BXGD015322 Midface retrusion
C1853482 BXGD015338 Pear-shaped nose
C1856266 BXGD015589 Coronal craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1858085 BXGD015770 Malar flattening
C1859461 BXGD015895 Femoral bowing Musculoskeletal Diseases
C1860042 BXGD015950 Antley-Bixler Syndrome with Disordered Steroidogenesis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C1860048 BXGD015951 Temporal bossing
C1860050 BXGD015952 Cloverleaf skull
C1865014 BXGD016282 Long philtrum
C1865847 BXGD016344 Ulnar bowing
C1866134 BXGD016378 Wide anterior fontanel
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2350233 BXGD017072 Antley-Bixler Syndrome Phenotype Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C2930865 BXGD017908 Ramer Ladda syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2936791 BXGD018138 Antley-Bixler Syndrome, Autosomal Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C3150099 BXGD018293 ANTLEY-BIXLER SYNDROME WITH GENITAL ANOMALIES AND DISORDERED STEROIDOGENESIS
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3854173 BXGD019824 Pre-renal acute kidney injury Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4020869 BXGD020489 Abnormality of abdomen morphology Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C4021124 BXGD020560 Adrenocorticotropic hormone excess Nervous System Diseases; Endocrine System Diseases
C4021551 BXGD020667 Absence of secondary sex characteristics
C4021740 BXGD020748 Increased circulating ACTH level
C4021768 BXGD020766 Abnormality of metabolism/homeostasis
C4021823 BXGD020808 Ambiguous genitalia, male Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C4021972 BXGD020849 Urogenital sinus anomaly
C4022554 BXGD020915 Hyperpigmented genitalia
C4022695 BXGD020962 Abnormality of the labia majora
C4022996 BXGD021057 Abnormal sex determination
C4024641 BXGD021355 Enlarged polycystic ovaries Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4024734 BXGD021394 Low maternal serum estriol
C4024735 BXGD021395 Maternal virilization in pregnancy
C4024878 BXGD021453 Generalized hyperpigmentation Skin and Connective Tissue Diseases
C4025823 BXGD021811 Abnormality of the endocrine system
C4025888 BXGD021848 Abnormality of the menstrual cycle Pathological Conditions, Signs and Symptoms
C4025891 BXGD021849 Ambiguous genitalia, female Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C4072885 BXGD022010 Increased serum testosterone level
C4073137 BXGD022045 Decreased serum testosterone level
C4551485 BXGD023312 Clinodactyly
C4551596 BXGD023368 Abnormal renal morphology
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0025206 Alpha-Lapachone 242.09
BXGC0028001 Beta-Lapachone 242.09
BXGC0035351 2-Acetyl Furanonapthoquinone 240.04
BXGC0039085 Dehydro-Alpha-Lapachone 240.08
BXGC0044200 Menadione 172.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein