Showing entry for Rho-related GTP-binding protein RhoQ


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008281
Protein NameRho-related GTP-binding protein RhoQ
Uniport IdP17081
GeneRHOQ
Gene Id23433
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.2 Endocrine system hsa04910 Insulin signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0016477 cell migration
Biological Process GO:0030031 cell projection assembly
Biological Process GO:0032869 cellular response to insulin stimulus
Biological Process GO:0030866 cortical actin cytoskeleton organization
Biological Process GO:0006897 endocytosis
Biological Process GO:0046039 GTP metabolic process
Biological Process GO:0008286 insulin receptor signaling pathway
Biological Process GO:1903077 negative regulation of protein localization to plasma membrane
Biological Process GO:0051491 positive regulation of filopodium assembly
Biological Process GO:0046326 positive regulation of glucose import
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0032956 regulation of actin cytoskeleton organization
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0051056 regulation of small GTPase mediated signal transduction
Biological Process GO:0007264 small GTPase mediated signal transduction
molecular function GO:0032427 GBD domain binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0005522 profilin binding
cellular component GO:0005884 actin filament
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0030660 Golgi-associated vesicle membrane
cellular component GO:0045121 membrane raft
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-HSA-162582 Signal Transduction
R-HSA-194315 Signaling by Rho GTPases
R-HSA-194840 Rho GTPase cycle
R-HSA-195258 RHO GTPase Effectors
R-HSA-199991 Membrane Trafficking
R-HSA-5627083 RHO GTPases regulate CFTR trafficking
R-HSA-5653656 Vesicle-mediated transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0200635 BXGD004041 Lymphocyte Count measurement
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0557874 BXGD009444 Global developmental delay
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein