Showing entry for Sphingomyelin phosphodiesterase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008304
Protein NameSphingomyelin phosphodiesterase
Uniport IdP17405
GeneSMPD1
Gene Id6609
DomainMetallophos
Pfam PF00149  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00600 Sphingolipid metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
3. Environmental Information Processing 3.2 Signal transduction hsa04071 Sphingolipid signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04142 Lysosome
4. Cellular Processes 4.2 Cell growth and death hsa04217 Necroptosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046513 ceramide biosynthetic process
Biological Process GO:0008203 cholesterol metabolic process
Biological Process GO:0006687 glycosphingolipid metabolic process
Biological Process GO:0043407 negative regulation of MAP kinase activity
Biological Process GO:0007399 nervous system development
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0035307 positive regulation of protein dephosphorylation
Biological Process GO:0042220 response to cocaine
Biological Process GO:0042493 response to drug
Biological Process GO:0007165 signal transduction
Biological Process GO:0006685 sphingomyelin catabolic process
Biological Process GO:0006684 sphingomyelin metabolic process
Biological Process GO:0023021 termination of signal transduction
molecular function GO:0061750 acid sphingomyelin phosphodiesterase activity
molecular function GO:0016798 hydrolase activity, acting on glycosyl bonds
molecular function GO:0008081 phosphoric diester hydrolase activity
molecular function GO:0004767 sphingomyelin phosphodiesterase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005768 endosome
cellular component GO:0070062 extracellular exosome
cellular component GO:0005615 extracellular space
cellular component GO:0042599 lamellar body
cellular component GO:0043202 lysosomal lumen
cellular component GO:0005764 lysosome
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1660662 Glycosphingolipid metabolism
R-HSA-428157 Sphingolipid metabolism
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002986 BXGD000165 Fabry Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0003635 BXGD000214 Apraxias Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004158 BXGD000261 Athetosis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004565 BXGD000276 Melanoma, B16 Neoplasms
C0004623 BXGD000282 Bacterial Infections Infections
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0008350 BXGD000531 Cholelithiasis Digestive System Diseases
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011875 BXGD000757 Diabetic Angiopathies Endocrine System Diseases; Cardiovascular Diseases
C0011882 BXGD000761 Diabetic Neuropathies Nervous System Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013404 BXGD000833 Dyspnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0016663 BXGD001071 Pathological fracture Wounds and Injuries
C0017205 BXGD001105 Gaucher Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019187 BXGD001296 Hepatitis, Alcoholic Digestive System Diseases; Chemically-Induced Disorders
C0019202 BXGD001302 Hepatolenticular Degeneration Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Nervous System Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0019214 BXGD001307 Hepatosplenomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Hemic and Lymphatic Diseases
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020532 BXGD001420 Hypersplenism Hemic and Lymphatic Diseases
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023461 BXGD001653 Leukemia, Mast-Cell Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023522 BXGD001680 Leukodystrophy, Metachromatic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0025521 BXGD001876 Inborn Errors of Metabolism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026837 BXGD001937 Muscle Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027626 BXGD002005 Neoplasm Invasiveness Pathological Conditions, Signs and Symptoms; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0028064 BXGD002068 Niemann-Pick Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0031511 BXGD002304 Pheochromocytoma Neoplasms
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0034012 BXGD002449 Delayed Puberty Endocrine System Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0035235 BXGD002519 Respiratory Syncytial Virus Infections Infections
C0036489 BXGD002620 Sea-Blue Histiocyte Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037899 BXGD002710 Sphingolipidoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0041234 BXGD002901 Chagas Disease Infections
C0041296 BXGD002903 Tuberculosis Infections
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0042963 BXGD003018 Vomiting Pathological Conditions, Signs and Symptoms
C0043325 BXGD003041 Xanthomatosis Nutritional and Metabolic Diseases
C0085078 BXGD003118 Lysosomal Storage Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0085129 BXGD003128 Bronchial Hyperreactivity Respiratory Tract Diseases
C0085131 BXGD003129 Gangliosidosis GM1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0085576 BXGD003188 Iron-Refractory Iron Deficiency Anemia Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0151691 BXGD003460 Decreased HDL cholesterol concentration Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0151888 BXGD003497 Hyporeflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0154251 BXGD003710 Lipid Metabolism Disorders Nutritional and Metabolic Diseases
C0155765 BXGD003819 Disease of capillaries Cardiovascular Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206062 BXGD004148 Lung Diseases, Interstitial Respiratory Tract Diseases
C0206656 BXGD004219 Embryonal Rhabdomyosarcoma Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220756 BXGD004338 Niemann-Pick Disease, Type C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0221013 BXGD004363 Mastocytosis, Systemic Neoplasms; Immune System Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0241654 BXGD005104 Abnormal heart valve morphology Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0242723 BXGD005193 Parasitemia Pathological Conditions, Signs and Symptoms; Infections
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0264716 BXGD005417 Chronic heart failure Cardiovascular Diseases
C0268070 BXGD005808 Hypocupremia
C0268242 BXGD005864 Niemann-Pick Disease, Type A Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0268243 BXGD005865 Niemann-Pick Disease, Type B Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0268248 BXGD005867 Niemann-Pick Disease, Type E Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0268255 BXGD005871 Farber Lipogranulomatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0276340 BXGD006419 Respiratory syncytial virus bronchiolitis Infections; Respiratory Tract Diseases
C0278484 BXGD006511 Malignant neoplasm of colon stage IV Digestive System Diseases; Neoplasms
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0332890 BXGD006909 Congenital hemihypertrophy Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0341439 BXGD007408 Chronic liver disease Digestive System Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0349588 BXGD007933 Short stature
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0398623 BXGD008202 Thrombophilia Hemic and Lymphatic Diseases
C0398650 BXGD008212 Immune thrombocytopenic purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0424230 BXGD008522 Motor retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0476337 BXGD008989 Blood gases abnormal
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0497156 BXGD009053 Lymphadenopathy Hemic and Lymphatic Diseases
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0541764 BXGD009259 Delayed bone age
C0549399 BXGD009376 Low density lipoprotein increased Nutritional and Metabolic Diseases
C0557874 BXGD009444 Global developmental delay
C0598608 BXGD009668 Hyperhomocysteinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677932 BXGD009736 Progressive Neoplastic Disease
C0694549 BXGD009851 Community acquired pneumonia Infections; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0849640 BXGD010889 skin damage
C0854135 BXGD011002 Pseudomonas aeruginosa infection Infections
C0856169 BXGD011096 Endothelial dysfunction
C0856825 BXGD011118 Acute GVH disease Immune System Diseases
C0876973 BXGD011322 Infectious Lung Disorder Infections; Respiratory Tract Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0920646 BXGD011471 Ischemia of kidney Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C1112486 BXGD011673 Aggressive Systemic Mastocytosis Neoplasms; Immune System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1397307 BXGD012996 Cardiac fibrosis
C1458140 BXGD013134 Bleeding tendency Hemic and Lymphatic Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1837658 BXGD014257 Gross motor development delay Mental Disorders
C1839839 BXGD014416 MAJOR AFFECTIVE DISORDER 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mental Disorders
C1843428 BXGD014583 Diffuse reticular or finely nodular infiltrations
C1849570 BXGD015067 Progressive pulmonary function impairment Respiratory Tract Diseases
C1852197 BXGD015264 MAJOR AFFECTIVE DISORDER 1 Mental Disorders
C1854928 BXGD015443 Protuberant abdomen
C1855179 BXGD015468 CATARACT, ANTERIOR POLAR Eye Diseases
C1856560 BXGD015617 Bone-marrow foam cells
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1859236 BXGD015867 Prolonged neonatal jaundice Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1866129 BXGD016375 Abnormality of the cerebellum Nervous System Diseases
C1866282 BXGD016393 CEROID LIPOFUSCINOSIS, NEURONAL, 6 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C1970943 BXGD016852 MAJOR AFFECTIVE DISORDER 4 Mental Disorders
C1970945 BXGD016853 MAJOR AFFECTIVE DISORDER 6 Mental Disorders
C2047520 BXGD016891 Mixed hyperlipidemia (disorder) Nutritional and Metabolic Diseases
C2216370 BXGD016949 Cherry red spot of the macula
C2674608 BXGD017250 Feeding difficulties in infancy
C2675646 BXGD017303 NIEMANN-PICK DISEASE, INTERMEDIATE, PROTRACTED NEUROVISCERAL (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C2700438 BXGD017469 MAJOR AFFECTIVE DISORDER 7 Mental Disorders
C2700439 BXGD017470 MAJOR AFFECTIVE DISORDER 8 Mental Disorders
C2700440 BXGD017471 MAJOR AFFECTIVE DISORDER 9 Mental Disorders
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2721740 BXGD017550 Ventilation perfusion mismatch
C2919142 BXGD017867 Short Stature, CTCAE
C2921627 BXGD017886 Clinically isolated syndrome
C2931687 BXGD018048 Dysferlinopathy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
C3160718 BXGD018468 PARKINSON DISEASE, LATE-ONSET
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C3539781 BXGD019086 Progressive cGVHD
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3805040 BXGD019456 Phospholipidosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C3806482 BXGD019514 Recurrent respiratory infections Infections; Respiratory Tract Diseases
C3828416 BXGD019740 Radiation Damage Wounds and Injuries
C4025279 BXGD021620 Respiratory failure requiring assisted ventilation Respiratory Tract Diseases
C4025590 BXGD021681 Foam cells with lamellar inclusion bodies
C4025790 BXGD021791 Specific learning disability
C4072897 BXGD022016 Decreased serum insulin-like growth factor 1
C4316903 BXGD022711 Absence Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4511452 BXGD023002 Sporadic Parkinson disease Nervous System Diseases
C4520679 BXGD023033 Abnormal macular morphology Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C4529962 BXGD023178 Fatty Liver Disease
C4551683 BXGD023389 Adrenal Gland Pheochromocytoma Neoplasms; Endocrine System Diseases
C4553743 BXGD023548 Spasticity, CTCAE
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
C4703473 BXGD023650 Atherosclerotic lesion Cardiovascular Diseases
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4732730 BXGD023895 Blood spots
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000189 7-Acetoxy-2-methylisoflavone 294.3
BXGC0000202 Papaverine 339.39
BXGC0000203 Piperine 285.34
BXGC0000292 Xanthotoxol 202.17
BXGC0000324 Isovitexin 432.38
BXGC0000952 6-Oxocamphor 457.91
BXGC0000999 Peucedanin 258.27
BXGC0001078 Xanthoangelol E 370.4
BXGC0001172 Xanthoangelol F 406.51
BXGC0001451 (S)-Laudanosine 357.44
BXGC0001545 Harmine 212.25
BXGC0001789 Silibinin 482.44
BXGC0001895 Cycloheterophyllin 502.56
BXGC0002064 Amentoflavone 538.46
BXGC0002144 Tetradecanoic acid 228.37
BXGC0002797 Nodakenetic 246.26
BXGC0003221 Xanthyletin 228.24
BXGC0003236 Neobyakangelicol 316.31
BXGC0003364 Cerebroside 299.49
BXGC0004497 3-O-Acetylepisamarcandin 442.54
BXGC0004747 trans-Sinapic acid 224.21
BXGC0004847 Dulxanthone D 342.34
BXGC0004955 N-Phenyl-2-naphthylamine 219.28
BXGC0005018 5,7-Dimethoxycoumarin 206.19
BXGC0005057 2-Methoxyxanthone 226.23
BXGC0005310 Moracin M 242.23
BXGC0005398 (-)-alpha-Narcotine 413.42
BXGC0005502 Coumestrol 268.22
BXGC0005624 Genistein 270.24
BXGC0005806 Glycyrol 366.36
BXGC0005846 Oroselone 226.23
BXGC0005852 Xanthoxyletin 258.27
BXGC0005907 7-Hydroxy-2-methylisoflavone 252.26
BXGC0005989 Auraptene 298.38
BXGC0006102 Methyl N-methylanthranilate 165.19
BXGC0007530 Folic acid 441.4
BXGC0007560 alpha-Mangostin 410.46
BXGC0009993 (R)-Mahanine 347.45
BXGC0011169 Moracin P 326.34
BXGC0011964 1,7-Dihydroxy-3,6-dimethoxy-2,8-diprenylxanthone 424.49
BXGC0014139 R-(+)-Marmin 332.16
BXGC0014695 Loratadine 382.14
BXGC0015351 Castanin 298.08
BXGC0015879 Chlorhexidine 504.2
BXGC0017158 thunberginol A 270.05
BXGC0018397 beta-1,4-mannan 180.06
BXGC0019962 Isoglycyrol 366.11
BXGC0020302 Hortiacine 317.12
BXGC0020756 4-(1,3-Benzothiazol-2-Yl)-2-Methylaniline 240.07
BXGC0021836 Honokiol 266.13
BXGC0022009 (9R)-9-[(9R)-2-Carboxy-4-Hydroxy-10-Oxo-5-[(3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-9H-Anthracen-9-Yl]-4-Hydroxy-10-Oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-9H-Anthracene-2-Carboxylic Acid 862.2
BXGC0022169 2-[(1S,6R)-6-(2,4-Dihydroxybenzoyl)-5-(2,4-Dihydroxyphenyl)-3-Methylcyclohex-2-En-1-Yl]-1,3,5A,8-Tetrahydroxy-10A-(3-Methylbut-2-Enyl)-[1]Benzofuro[3,2-B]Chromen-11-One 708.22
BXGC0022621 3-[(2S)-5,7-Dihydroxy-2-(4-Hydroxyphenyl)-3,4-Dihydro-2H-Chromen-8-Yl]-5,7-Dihydroxy-2-(4-Hydroxyphenyl)Chromen-4-One 526.13
BXGC0024331 7-O-Ac-afromosin 340.09
BXGC0025757 Calcimycin 523.27
BXGC0026480 Osajin 404.16
BXGC0029291 Diphyllin 380.09
BXGC0029807 Anisocoumarin H 314.15
BXGC0030696 2,3-Dimethoxyxanthen-9-One 256.07
BXGC0030879 Mesodihydroguaiaretic Acid 330.18
BXGC0031233 Umbelliprenin 366.22
BXGC0034006 Fluoranthene 202.08
BXGC0035557 Pratol 268.07
BXGC0037722 Pomiferin 420.16
BXGC0038197 2-Methoxyphenazine 210.08
BXGC0038638 Gerontoxanthone A 394.14
BXGC0039019 Harmol 198.08
BXGC0039172 Oxyresveratrol 244.07
BXGC0039670 Nodakenin 408.14
BXGC0041676 Pentamethylquercetin 372.12
BXGC0042035 raubasine 352.18
BXGC0042046 Actinodaphnine 311.12
BXGC0042107 Methyl 18-Hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-Dodecahydroyohimban-19-Carboxylate 354.19
BXGC0042336 7-Amino-4-Hydroxynaphthalene-2-Sulfonic Acid 239.03
BXGC0042738 Columbianetin 246.09
BXGC0042832 Cistanoside D 652.24
BXGC0042870 Piceatannol 244.07
BXGC0043682 cowanin 478.24
BXGC0044256 37497-84-0 203.06
BXGC0044857 Sp-600125 220.06
BXGC0046862 Benzo[Def]Chrysene 252.09
BXGC0048895 Picrasidine O 280.08
BXGC0049049 Haplamine 257.11
BXGC0049050 baohuoside II 500.17
BXGC0049447 acetate 59.01
BXGC0050194 alpha-D-Mannose 180.06
BXGC0050284 10-Hydroxycamptothecin 364.11
BXGC0051013 N-Phenylnaphthalen-1-Amine 219.1
BXGC0053259 Liriodendrtachioside 742.27
BXGC0053274 4-(2,3-Dihydroxy-3-Methylbutoxy)Furo[3,2-G]Chromen-7-One 304.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein