Showing entry for Chymotrypsinogen B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008314
Protein NameChymotrypsinogen B
Uniport IdP17538
GeneCTRB1
Gene Id1504
DomainTrypsin
Pfam PF00089  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.4 Digestive system hsa04972 Pancreatic secretion
5. Organismal Systems 5.4 Digestive system hsa04974 Protein digestion and absorption
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009235 cobalamin metabolic process
Biological Process GO:0007586 digestion
Biological Process GO:0022617 extracellular matrix disassembly
Biological Process GO:0006508 proteolysis
molecular function GO:0004252 serine-type endopeptidase activity
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1474228 Degradation of the extracellular matrix
R-HSA-1474244 Extracellular matrix organization
R-HSA-1592389 Activation of Matrix Metalloproteinases
R-HSA-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism
R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
R-HSA-196854 Metabolism of vitamins and cofactors
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002893 BXGD000150 Refractory anemias Hemic and Lymphatic Diseases
C0003129 BXGD000182 Anoxemia Pathological Conditions, Signs and Symptoms
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0030305 BXGD002206 Pancreatitis Digestive System Diseases
C0149521 BXGD003328 Pancreatitis, Chronic Digestive System Diseases
C0242184 BXGD005140 Hypoxia Pathological Conditions, Signs and Symptoms
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0376670 BXGD008007 Pancreatitis, Alcoholic Digestive System Diseases; Chemically-Induced Disorders
C0700292 BXGD009884 Hypoxemia Pathological Conditions, Signs and Symptoms
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2985280 BXGD018223 Blood Protein Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005683 Quercetin 302.24
BXGC0005702 2H-1-Benzopyran-2-one 146.15
BXGC0027547 Indigo 262.07
BXGC0034256 Rottlerin 516.18
BXGC0040042 Warfarin 308.1
BXGC0040305 Indirubin 262.07
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein