Showing entry for cAMP-dependent protein kinase catalytic subunit alpha



                       
General Target Information
BXGT IdBXGT008322
Protein NamecAMP-dependent protein kinase catalytic subunit alpha
Uniport IdP17612
GenePRKACA
Gene Id5566
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.12 Drug resistance: Antineoplastic hsa01522 Endocrine resistance
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04014 Ras signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04024 cAMP signaling pathway
5. Organismal Systems 5.1 Immune system hsa04062 Chemokine signaling pathway
4. Cellular Processes 4.2 Cell growth and death hsa04114 Oocyte meiosis
4. Cellular Processes 4.1 Transport and catabolism hsa04140 Autophagy - animal
5. Organismal Systems 5.9 Aging hsa04211 Longevity regulating pathway
5. Organismal Systems 5.9 Aging hsa04213 Longevity regulating pathway - multiple species
5. Organismal Systems 5.3 Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes
5. Organismal Systems 5.3 Circulatory system hsa04270 Vascular smooth muscle contraction
3. Environmental Information Processing 3.2 Signal transduction hsa04310 Wnt signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04340 Hedgehog signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04371 Apelin signaling pathway
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04540 Gap junction
5. Organismal Systems 5.1 Immune system hsa04611 Platelet activation
5. Organismal Systems 5.10 Environmental adaptation hsa04713 Circadian entrainment
5. Organismal Systems 5.10 Environmental adaptation hsa04714 Thermogenesis
5. Organismal Systems 5.6 Nervous system hsa04720 Long-term potentiation
5. Organismal Systems 5.6 Nervous system hsa04723 Retrograde endocannabinoid signaling
5. Organismal Systems 5.6 Nervous system hsa04724 Glutamatergic synapse
5. Organismal Systems 5.6 Nervous system hsa04725 Cholinergic synapse
5. Organismal Systems 5.6 Nervous system hsa04726 Serotonergic synapse
5. Organismal Systems 5.6 Nervous system hsa04727 GABAergic synapse
5. Organismal Systems 5.6 Nervous system hsa04728 Dopaminergic synapse
5. Organismal Systems 5.7 Sensory system hsa04740 Olfactory transduction
5. Organismal Systems 5.7 Sensory system hsa04742 Taste transduction
5. Organismal Systems 5.7 Sensory system hsa04750 Inflammatory mediator regulation of TRP channels
5. Organismal Systems 5.2 Endocrine system hsa04910 Insulin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04911 Insulin secretion
5. Organismal Systems 5.2 Endocrine system hsa04912 GnRH signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04913 Ovarian steroidogenesis
5. Organismal Systems 5.2 Endocrine system hsa04914 Progesterone-mediated oocyte maturation
5. Organismal Systems 5.2 Endocrine system hsa04915 Estrogen signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04916 Melanogenesis
5. Organismal Systems 5.2 Endocrine system hsa04918 Thyroid hormone synthesis
5. Organismal Systems 5.2 Endocrine system hsa04919 Thyroid hormone signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04921 Oxytocin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04922 Glucagon signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04923 Regulation of lipolysis in adipocytes
5. Organismal Systems 5.2 Endocrine system hsa04924 Renin secretion
5. Organismal Systems 5.2 Endocrine system hsa04925 Aldosterone synthesis and secretion
5. Organismal Systems 5.2 Endocrine system hsa04926 Relaxin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04927 Cortisol synthesis and secretion
5. Organismal Systems 5.2 Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04934 Cushing syndrome
5. Organismal Systems 5.5 Excretory system hsa04961 Endocrine and other factor-regulated calcium reabsorption
5. Organismal Systems 5.5 Excretory system hsa04962 Vasopressin-regulated water reabsorption
5. Organismal Systems 5.4 Digestive system hsa04970 Salivary secretion
5. Organismal Systems 5.4 Digestive system hsa04971 Gastric acid secretion
5. Organismal Systems 5.4 Digestive system hsa04976 Bile secretion
6. Human Diseases 6.4 Neurodegenerative diseases hsa05012 Parkinson disease
6. Human Diseases 6.4 Neurodegenerative diseases hsa05020 Prion diseases
6. Human Diseases 6.5 Substance dependence hsa05030 Cocaine addiction
6. Human Diseases 6.5 Substance dependence hsa05031 Amphetamine addiction
6. Human Diseases 6.5 Substance dependence hsa05032 Morphine addiction
6. Human Diseases 6.5 Substance dependence hsa05034 Alcoholism
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05110 Vibrio cholerae infection
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05146 Amoebiasis
6. Human Diseases 6.9 Infectious diseases: Viral hsa05163 Human cytomegalovirus infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05165 Human papillomavirus infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05166 Human T-cell leukemia virus 1 infection
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.1 Cancers: Overview hsa05203 Viral carcinogenesis
6. Human Diseases 6.1 Cancers: Overview hsa05205 Proteoglycans in cancer
6. Human Diseases 6.6 Cardiovascular diseases hsa05414 Dilated cardiomyopathy (DCM)
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034199 activation of protein kinase A activity
Biological Process GO:0007596 blood coagulation
Biological Process GO:0035584 calcium-mediated signaling using intracellular calcium source
Biological Process GO:0086064 cell communication by electrical coupling involved in cardiac conduction
Biological Process GO:0071872 cellular response to epinephrine stimulus
Biological Process GO:0071377 cellular response to glucagon stimulus
Biological Process GO:0071333 cellular response to glucose stimulus
Biological Process GO:0034605 cellular response to heat
Biological Process GO:0071374 cellular response to parathyroid hormone stimulus
Biological Process GO:0097711 ciliary basal body-plasma membrane docking
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0000086 G2/M transition of mitotic cell cycle
Biological Process GO:0034380 high-density lipoprotein particle assembly
Biological Process GO:0001707 mesoderm formation
Biological Process GO:0050804 modulation of chemical synaptic transmission
Biological Process GO:0006397 mRNA processing
Biological Process GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
Biological Process GO:0001843 neural tube closure
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0018107 peptidyl-threonine phosphorylation
Biological Process GO:0071158 positive regulation of cell cycle arrest
Biological Process GO:0046827 positive regulation of protein export from nucleus
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0010737 protein kinase A signaling
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:2000810 regulation of bicellular tight junction assembly
Biological Process GO:1903779 regulation of cardiac conduction
Biological Process GO:0055117 regulation of cardiac muscle contraction
Biological Process GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
Biological Process GO:0051480 regulation of cytosolic calcium ion concentration
Biological Process GO:0010389 regulation of G2/M transition of mitotic cell cycle
Biological Process GO:0002027 regulation of heart rate
Biological Process GO:0016241 regulation of macroautophagy
Biological Process GO:0045667 regulation of osteoblast differentiation
Biological Process GO:0061136 regulation of proteasomal protein catabolic process
Biological Process GO:0043393 regulation of protein binding
Biological Process GO:0070613 regulation of protein processing
Biological Process GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity
Biological Process GO:0003091 renal water homeostasis
Biological Process GO:0048240 sperm capacitation
Biological Process GO:0002223 stimulatory C-type lectin receptor signaling pathway
molecular function GO:0004679 AMP-activated protein kinase activity
molecular function GO:0005524 ATP binding
molecular function GO:0004691 cAMP-dependent protein kinase activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0030145 manganese ion binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0034237 protein kinase A regulatory subunit binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0004712 protein serine/threonine/tyrosine kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0031625 ubiquitin protein ligase binding
cellular component GO:0001669 acrosomal vesicle
cellular component GO:0034704 calcium channel complex
cellular component GO:0005952 cAMP-dependent protein kinase complex
cellular component GO:0005813 centrosome
cellular component GO:0097546 ciliary base
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0043197 dendritic spine
cellular component GO:0070062 extracellular exosome
cellular component GO:0045171 intercellular bridge
cellular component GO:0016020 membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0031594 neuromuscular junction
cellular component GO:0016607 nuclear speck
cellular component GO:0005654 nucleoplasm
cellular component GO:0031588 nucleotide-activated protein kinase complex
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0044853 plasma membrane raft
cellular component GO:0036126 sperm flagellum
cellular component GO:0097225 sperm midpiece
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-111885 Opioid Signalling
R-HSA-111885 Opioid Signalling
R-HSA-111931 PKA-mediated phosphorylation of CREB
R-HSA-111931 PKA-mediated phosphorylation of CREB
R-HSA-111933 Calmodulin induced events
R-HSA-111933 Calmodulin induced events
R-HSA-111996 Ca-dependent events
R-HSA-111996 Ca-dependent events
R-HSA-111997 CaM pathway
R-HSA-111997 CaM pathway
R-HSA-112040 G-protein mediated events
R-HSA-112040 G-protein mediated events
R-HSA-112043 PLC beta mediated events
R-HSA-112043 PLC beta mediated events
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-112316 Neuronal System
R-HSA-1266738 Developmental Biology
R-HSA-1266738 Developmental Biology
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1280218 Adaptive Immune System
R-HSA-1430728 Metabolism
R-HSA-1430728 Metabolism
R-HSA-1489509 DAG and IP3 signaling
R-HSA-1489509 DAG and IP3 signaling
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-163358 PKA-mediated phosphorylation of key metabolic factors
R-HSA-163359 Glucagon signaling in metabolic regulation
R-HSA-163560 Triglyceride catabolism
R-HSA-163615 PKA activation
R-HSA-163685 Integration of energy metabolism
R-HSA-163685 Integration of energy metabolism
R-HSA-1640170 Cell Cycle
R-HSA-1643685 Disease
R-HSA-1643685 Disease
R-HSA-164378 PKA activation in glucagon signalling
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-174824 Plasma lipoprotein assembly, remodeling, and clearance
R-HSA-180024 DARPP-32 events
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-194138 Signaling by VEGF
R-HSA-212436 Generic Transcription Pathway
R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition
R-HSA-372790 Signaling by GPCR
R-HSA-372790 Signaling by GPCR
R-HSA-376176 Signaling by ROBO receptors
R-HSA-380259 Loss of Nlp from mitotic centrosomes
R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes
R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome
R-HSA-380287 Centrosome maturation
R-HSA-380320 Recruitment of NuMA to mitotic centrosomes
R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
R-HSA-382551 Transport of small molecules
R-HSA-388396 GPCR downstream signalling
R-HSA-388396 GPCR downstream signalling
R-HSA-392517 Rap1 signalling
R-HSA-397014 Muscle contraction
R-HSA-418594 G alpha (i) signalling events
R-HSA-418594 G alpha (i) signalling events
R-HSA-422356 Regulation of insulin secretion
R-HSA-422356 Regulation of insulin secretion
R-HSA-422475 Axon guidance
R-HSA-422475 Axon guidance
R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins
R-HSA-438064 Post NMDA receptor activation events
R-HSA-438064 Post NMDA receptor activation events
R-HSA-4420097 VEGFA-VEGFR2 Pathway
R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase
R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-445717 Aquaporin-mediated transport
R-HSA-449147 Signaling by Interleukins
R-HSA-453274 Mitotic G2-G2/M phases
R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling
R-HSA-5358351 Signaling by Hedgehog
R-HSA-5358351 Signaling by Hedgehog
R-HSA-556833 Metabolism of lipids
R-HSA-5576891 Cardiac conduction
R-HSA-5578775 Ion homeostasis
R-HSA-5610780 Degradation of GLI1 by the proteasome
R-HSA-5610783 Degradation of GLI2 by the proteasome
R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome
R-HSA-5610787 Hedgehog 'off' state
R-HSA-5610787 Hedgehog 'off' state
R-HSA-5617833 Cilium Assembly
R-HSA-5620912 Anchoring of the basal body to the plasma membrane
R-HSA-5621481 C-type lectin receptors (CLRs)
R-HSA-5621575 CD209 (DC-SIGN) signaling
R-HSA-5663205 Infectious disease
R-HSA-5663205 Infectious disease
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5687128 MAPK6/MAPK4 signaling
R-HSA-68877 Mitotic Prometaphase
R-HSA-68886 M Phase
R-HSA-69275 G2/M Transition
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-70171 Glycolysis
R-HSA-70326 Glucose metabolism
R-HSA-71387 Metabolism of carbohydrates
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-8853659 RET signaling
R-HSA-8854518 AURKA Activation by TPX2
R-HSA-8963896 HDL assembly
R-HSA-8963898 Plasma lipoprotein assembly
R-HSA-8979227 Triglyceride metabolism
R-HSA-8986944 Transcriptional Regulation by MECP2
R-HSA-9005891 Loss of function of MECP2 in Rett syndrome
R-HSA-9005895 Pervasive developmental disorders
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-9010642 ROBO receptors bind AKAP5
R-HSA-9022535 Loss of phosphorylation of MECP2 at T308
R-HSA-9022692 Regulation of MECP2 expression and activity
R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
R-HSA-9658195 Leishmania infection
R-HSA-9658195 Leishmania infection
R-HSA-9660821 ADORA2B mediated anti-inflammatory cytokines production
R-HSA-9660821 ADORA2B mediated anti-inflammatory cytokines production
R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection
R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection
R-HSA-9664323 FCGR3A-mediated IL10 synthesis
R-HSA-9664323 FCGR3A-mediated IL10 synthesis
R-HSA-9664433 Leishmania parasite growth and survival
R-HSA-9664433 Leishmania parasite growth and survival
R-HSA-9675108 Nervous system development
R-HSA-9675108 Nervous system development
R-HSA-9675151 Disorders of Developmental Biology
R-HSA-9697154 Disorders of Nervous System Development
R-HSA-983231 Factors involved in megakaryocyte development and platelet production
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0001622 BXGD000065 Adrenal Gland Hyperfunction Endocrine System Diseases
C0001624 BXGD000067 Adrenal Gland Neoplasms Neoplasms; Endocrine System Diseases
C0001627 BXGD000068 Congenital adrenal hyperplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0002170 BXGD000105 Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0010481 BXGD000673 Cushing Syndrome Endocrine System Diseases
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0019572 BXGD001338 Hirsutism Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020619 BXGD001447 Hypogonadism Endocrine System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0032002 BXGD002320 Pituitary Diseases Nervous System Diseases; Endocrine System Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0043094 BXGD003026 Weight Gain Pathological Conditions, Signs and Symptoms
C0085633 BXGD003216 Mood swings Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0152459 BXGD003600 Linear atrophy Pathological Conditions, Signs and Symptoms
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0206667 BXGD004228 Adrenal Cortical Adenoma Neoplasms; Endocrine System Diseases
C0206686 BXGD004241 Adrenocortical carcinoma Neoplasms; Endocrine System Diseases
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0221406 BXGD004459 Pituitary-dependent Cushing's disease Nervous System Diseases; Endocrine System Diseases
C0221629 BXGD004467 Proximal muscle weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0241181 BXGD005084 Fragile skin
C0262401 BXGD005235 Carcinoma of ampulla of Vater Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0262929 BXGD005269 Myxoma of the Endocardium Neoplasms
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0332601 BXGD006896 Cushingoid facies Endocrine System Diseases
C0334287 BXGD007022 Fibrolamellar Hepatocellular Carcinoma Digestive System Diseases; Neoplasms
C0342418 BXGD007478 Hypothalamic hamartomas Neoplasms; Nervous System Diseases
C0342443 BXGD007481 Adrenal Cushing's syndrome Endocrine System Diseases
C0342496 BXGD007491 Micronodular adrenal hyperplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0349588 BXGD007933 Short stature
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0423757 BXGD008504 Thin skin
C0423798 BXGD008510 Increased tendency to bruise Wounds and Injuries
C0520573 BXGD009094 Buffalo hump
C0541794 BXGD009262 Skeletal muscle atrophy
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0702166 BXGD009912 Acne Skin and Connective Tissue Diseases
C0750887 BXGD010240 Adrenal Cancer Neoplasms; Endocrine System Diseases
C0858864 BXGD011194 Spot pigmented
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306214 BXGD012356 ACTH-Secreting Pituitary Adenoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1384514 BXGD012940 Conn Syndrome Endocrine System Diseases
C1390474 BXGD012969 Increased susceptibility to fractures
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1621895 BXGD013466 Adrenal hyperplasia Pathological Conditions, Signs and Symptoms; Neoplasms; Endocrine System Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1850573 BXGD015154 Slender build Pathological Conditions, Signs and Symptoms
C1857451 BXGD015702 Acth-Independent Macronodular Adrenal Hyperplasia Endocrine System Diseases
C1960546 BXGD016667 Myxoma of heart Neoplasms; Cardiovascular Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1968851 BXGD016741 Pigmented micronodular adrenocortical disease
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2919142 BXGD017867 Short Stature, CTCAE
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C3805278 BXGD019474 Extrahepatic Cholangiocarcinoma Neoplasms
C4014425 BXGD020145 PIGMENTED NODULAR ADRENOCORTICAL DISEASE, PRIMARY, 4
C4025760 BXGD021781 Primary hypercortisolism
C4304832 BXGD022585 Primary pigmented nodular adrenocortical disease
C4727458 BXGD023864 Metastatic Fibrolamellar Carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000116 1,4-Naphtoquinone 158.15
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0000536 Phenol 94.11
BXGC0000655 Harmalol 200.24
BXGC0000933 (-)-Arctigenin 372.41
BXGC0001544 Harmaline 214.26
BXGC0001545 Harmine 212.25
BXGC0001940 Daphnetin 178.14
BXGC0002071 Apigenin 270.24
BXGC0002144 Tetradecanoic acid 228.37
BXGC0002392 Pentanal 86.13
BXGC0002588 Magnesium 24.31
BXGC0004115 Norharman 168.19
BXGC0005624 Genistein 270.24
BXGC0005683 Quercetin 302.24
BXGC0006193 Ellagic acid 302.19
BXGC0007014 Harman 182.22
BXGC0007029 Emodin 270.24
BXGC0007052 Olomoucine 298.34
BXGC0012352 Chelerythrine 348.12
BXGC0012706 4-hydroxy-5-nitrophenyl acetic acid 197.03
BXGC0013109 4-[2-(3,5-Dihydroxyphenyl)Ethenyl]Benzene-1,2-Diol 244.07
BXGC0013582 Curcumin 368.13
BXGC0020911 Debromohymenialdisine 245.09
BXGC0023872 Adenine 135.05
BXGC0032694 1-Phenylprop-2-En-1-One 132.06
BXGC0034256 Rottlerin 516.18
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0042409 2-Bromo-1-Phenylethanone 197.97
BXGC0042870 Piceatannol 244.07
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0046919 debromohymenialdisine 245.09
BXGC0047575 (2S,3S)-butane-2,3-diol 90.07
BXGC0047576 4-hydroxy-3-methylacetophenone 150.07
BXGC0047692 Gefitinib 446.15
BXGC0049447 acetate 59.01
BXGC0051873 Sl-0101 516.13
BXGC0051995 Wedelolactone 314.04
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein