Showing entry for Beta-arrestin-1



                       
General Target Information
BXGT IdBXGT008350
Protein NameBeta-arrestin-1
Uniport IdP17870
GeneARRB1
Gene Id281637
DomainArrestin_C; Arrestin_N
Pfam PF02752   PF00339  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0072583 clathrin-dependent endocytosis
Biological Process GO:0002029 desensitization of G protein-coupled receptor signaling pathway
Biological Process GO:0002031 G protein-coupled receptor internalization
Biological Process GO:0045746 negative regulation of Notch signaling pathway
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0002092 positive regulation of receptor internalization
Biological Process GO:0015031 protein transport
Biological Process GO:0031623 receptor internalization
Biological Process GO:0007165 signal transduction
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process
molecular function GO:0033130 acetylcholine receptor binding
molecular function GO:0035612 AP-2 adaptor complex binding
molecular function GO:0030276 clathrin binding
molecular function GO:0032050 clathrin heavy chain binding
molecular function GO:0001664 G protein-coupled receptor binding
molecular function GO:0000822 inositol hexakisphosphate binding
molecular function GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
cellular component GO:0030132 clathrin coat of coated pit
cellular component GO:0005737 cytoplasm
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005829 cytosol
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0031143 pseudopodium
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000140 Phytic acid 660.04
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein