Showing entry for ADP-ribosylation factor 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008377
Protein NameADP-ribosylation factor 4
Uniport IdP18085
GeneARF4
Gene Id378
DomainArf
Pfam PF00025  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031584 activation of phospholipase D activity
Biological Process GO:0045176 apical protein localization
Biological Process GO:0007420 brain development
Biological Process GO:0016477 cell migration
Biological Process GO:0060996 dendritic spine development
Biological Process GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Biological Process GO:0007173 epidermal growth factor receptor signaling pathway
Biological Process GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0007612 learning
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0006471 protein ADP-ribosylation
Biological Process GO:0061512 protein localization to cilium
Biological Process GO:0099175 regulation of postsynapse organization
Biological Process GO:2000377 regulation of reactive oxygen species metabolic process
Biological Process GO:0048678 response to axon injury
Biological Process GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
Biological Process GO:0016192 vesicle-mediated transport
molecular function GO:0005086 ARF guanyl-nucleotide exchange factor activity
molecular function GO:0005154 epidermal growth factor receptor binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0043197 dendritic spine
cellular component GO:0070062 extracellular exosome
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005794 Golgi apparatus
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0032587 ruffle membrane
Reactome
Pathway Id Pathway Name
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-199977 ER to Golgi Anterograde Transport
R-HSA-199991 Membrane Trafficking
R-HSA-392499 Metabolism of proteins
R-HSA-446203 Asparagine N-linked glycosylation
R-HSA-5617833 Cilium Assembly
R-HSA-5617833 Cilium Assembly
R-HSA-5620916 VxPx cargo-targeting to cilium
R-HSA-5620916 VxPx cargo-targeting to cilium
R-HSA-5620920 Cargo trafficking to the periciliary membrane
R-HSA-5620920 Cargo trafficking to the periciliary membrane
R-HSA-5653656 Vesicle-mediated transport
R-HSA-597592 Post-translational protein modification
R-HSA-6807878 COPI-mediated anterograde transport
R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic
R-HSA-8856688 Golgi-to-ER retrograde transport
R-HSA-948021 Transport to the Golgi and subsequent modification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0022679 BXGD001575 Cystic kidney Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0311245 BXGD006869 Congenital cystic kidney disease Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1691228 BXGD013492 Cystic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4290046 BXGD022507 trachomatis
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein