protein

Showing entry for Glycogen synthase kinase-3 alpha

General Target Information
BXGT Id	BXGT008393
Protein Name	Glycogen synthase kinase-3 alpha
Uniport Id	P18265
Gene	Gsk3a
Gene Id	50686
Domain	Pkinase
Pfam	PF00069
Organism	Rattus norvegicus (Rat)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0007568	aging
Biological Process	GO:0003214	cardiac left ventricle morphogenesis
Biological Process	GO:0016477	cell migration
Biological Process	GO:0032869	cellular response to insulin stimulus
Biological Process	GO:0036016	cellular response to interleukin-3
Biological Process	GO:0071285	cellular response to lithium ion
Biological Process	GO:0071407	cellular response to organic cyclic compound
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
Biological Process	GO:0005977	glycogen metabolic process
Biological Process	GO:0044027	hypermethylation of CpG island
Biological Process	GO:0008286	insulin receptor signaling pathway
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway
Biological Process	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development
Biological Process	GO:2000171	negative regulation of dendrite development
Biological Process	GO:0046325	negative regulation of glucose import
Biological Process	GO:1904227	negative regulation of glycogen synthase activity, transferring glucose-1-phosphate
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway
Biological Process	GO:0032007	negative regulation of TOR signaling
Biological Process	GO:0018105	peptidyl-serine phosphorylation
Biological Process	GO:0018107	peptidyl-threonine phosphorylation
Biological Process	GO:0071879	positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway
Biological Process	GO:0106071	positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process	GO:1902004	positive regulation of amyloid-beta formation
Biological Process	GO:0010508	positive regulation of autophagy
Biological Process	GO:0010628	positive regulation of gene expression
Biological Process	GO:2000467	positive regulation of glycogen (starch) synthase activity
Biological Process	GO:0045823	positive regulation of heart contraction
Biological Process	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
Biological Process	GO:0043525	positive regulation of neuron apoptotic process
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation
Biological Process	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Biological Process	GO:1903955	positive regulation of protein targeting to mitochondrion
Biological Process	GO:0031398	positive regulation of protein ubiquitination
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
Biological Process	GO:0006468	protein phosphorylation
Biological Process	GO:1903146	regulation of autophagy of mitochondrion
Biological Process	GO:0006349	regulation of gene expression by genetic imprinting
Biological Process	GO:0010975	regulation of neuron projection development
Biological Process	GO:0003073	regulation of systemic arterial blood pressure
Biological Process	GO:0007165	signal transduction
Biological Process	GO:0016055	Wnt signaling pathway
molecular function	GO:0005524	ATP binding
molecular function	GO:0034236	protein kinase A catalytic subunit binding
molecular function	GO:0004672	protein kinase activity
molecular function	GO:0019901	protein kinase binding
molecular function	GO:0004674	protein serine/threonine kinase activity
molecular function	GO:0005102	signaling receptor binding
molecular function	GO:0050321	tau-protein kinase activity
cellular component	GO:0030424	axon
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005829	cytosol
cellular component	GO:0005874	microtubule
cellular component	GO:0005739	mitochondrion
cellular component	GO:0005634	nucleus

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0006389	Rotenone		394.42

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}