Showing entry for Integrin alpha-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008416
Protein NameIntegrin alpha-1
Uniport IdP18614
GeneItga1
Gene Id25118
DomainFG-GAP; Integrin_alpha2; VWA
Pfam PF01839   PF08441   PF00092  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0007155 cell adhesion
Biological Process GO:0060326 cell chemotaxis
Biological Process GO:0007160 cell-matrix adhesion
Biological Process GO:0045123 cellular extravasation
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
Biological Process GO:0048812 neuron projection morphogenesis
Biological Process GO:0030593 neutrophil chemotaxis
Biological Process GO:0043525 positive regulation of neuron apoptotic process
Biological Process GO:0032516 positive regulation of phosphoprotein phosphatase activity
Biological Process GO:0042311 vasodilation
molecular function GO:0005518 collagen binding
molecular function GO:0098639 collagen binding involved in cell-matrix adhesion
molecular function GO:0046872 metal ion binding
molecular function GO:0019903 protein phosphatase binding
molecular function GO:0005102 signaling receptor binding
cellular component GO:0001669 acrosomal vesicle
cellular component GO:0045178 basal part of cell
cellular component GO:0009986 cell surface
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005925 focal adhesion
cellular component GO:0034665 integrin alpha1-beta1 complex
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0043005 neuron projection
cellular component GO:0043204 perikaryon
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein