Showing entry for Alpha-2B adrenergic receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008473
Protein NameAlpha-2B adrenergic receptor
Uniport IdP19328
GeneAdra2b
Gene Id24174
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0032148 activation of protein kinase B activity
Biological Process GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0071875 adrenergic receptor signaling pathway
Biological Process GO:0001525 angiogenesis
Biological Process GO:0007565 female pregnancy
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0000165 MAPK cascade
Biological Process GO:0030168 platelet activation
Biological Process GO:0045777 positive regulation of blood pressure
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0045666 positive regulation of neuron differentiation
Biological Process GO:0070474 positive regulation of uterine smooth muscle contraction
Biological Process GO:0035624 receptor transactivation
Biological Process GO:0003056 regulation of vascular associated smooth muscle contraction
molecular function GO:0004935 adrenergic receptor activity
molecular function GO:0004938 alpha2-adrenergic receptor activity
molecular function GO:0051379 epinephrine binding
molecular function GO:0004930 G protein-coupled receptor activity
cellular component GO:0009986 cell surface
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000538 (R)-Norepinephrine 169.18
BXGC0000548 Tryptamine 160.22
BXGC0000564 1H-Indole-3-methanamine 146.19
BXGC0003196 Aripiprazole 448.39
BXGC0004285 Agmatine 130.19
BXGC0004763 Octopamine 153.18
BXGC0005794 Benzylamine 107.15
BXGC0005871 Dopamine 153.18
BXGC0012888 2-Methyl-3,4-Dihydro-1H-Isoquinoline 147.1
BXGC0017443 Phenylephrine 167.09
BXGC0021210 Phenylpropanolamine 151.1
BXGC0021893 Norepinephrine 169.07
BXGC0027118 Tamsulosin 408.17
BXGC0031384 Epinephrine 183.09
BXGC0033862 Akuammigine 352.18
BXGC0034371 1,2,3,4-Tetrahydroisoquinoline 133.09
BXGC0042035 raubasine 352.18
BXGC0042222 Propranolol 259.16
BXGC0042510 Fluoxetine 309.13
BXGC0043126 Nicardipine 479.21
BXGC0046755 Yohimbine 354.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein