Showing entry for Casein kinase II subunit alpha'


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008513
Protein NameCasein kinase II subunit alpha'
Uniport IdP19784
GeneCSNK2A2
Gene Id1459
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa03008 Ribosome biogenesis in eukaryotes
3. Environmental Information Processing 3.2 Signal transduction hsa04064 NF-kappa B signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04137 Mitophagy - animal
3. Environmental Information Processing 3.2 Signal transduction hsa04310 Wnt signaling pathway
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04520 Adherens junction
6. Human Diseases 6.9 Infectious diseases: Viral hsa05162 Measles
6. Human Diseases 6.1 Cancers: Overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0007049 cell cycle
Biological Process GO:0021987 cerebral cortex development
Biological Process GO:0097421 liver regeneration
Biological Process GO:0016236 macroautophagy
Biological Process GO:2001234 negative regulation of apoptotic signaling pathway
Biological Process GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0018107 peptidyl-threonine phosphorylation
Biological Process GO:0006656 phosphatidylcholine biosynthetic process
Biological Process GO:1903955 positive regulation of protein targeting to mitochondrion
Biological Process GO:0006457 protein folding
Biological Process GO:1903146 regulation of autophagy of mitochondrion
Biological Process GO:0051726 regulation of cell cycle
Biological Process GO:1905818 regulation of chromosome separation
Biological Process GO:1901796 regulation of signal transduction by p53 class mediator
Biological Process GO:0007283 spermatogenesis
Biological Process GO:0016055 Wnt signaling pathway
molecular function GO:0005524 ATP binding
molecular function GO:0047485 protein N-terminus binding
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0001669 acrosomal vesicle
cellular component GO:0000785 chromatin
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0005956 protein kinase CK2 complex
Reactome
Pathway Id Pathway Name
R-HSA-1257604 PIP3 activates AKT signaling
R-HSA-1266738 Developmental Biology
R-HSA-1430728 Metabolism
R-HSA-1483191 Synthesis of PC
R-HSA-1483206 Glycerophospholipid biosynthesis
R-HSA-1483257 Phospholipid metabolism
R-HSA-162582 Signal Transduction
R-HSA-1632852 Macroautophagy
R-HSA-1640170 Cell Cycle
R-HSA-195721 Signaling by WNT
R-HSA-201681 TCF dependent signaling in response to WNT
R-HSA-201688 WNT mediated activation of DVL
R-HSA-212436 Generic Transcription Pathway
R-HSA-2514853 Condensation of Prometaphase Chromosomes
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-373760 L1CAM interactions
R-HSA-390466 Chaperonin-mediated protein folding
R-HSA-391251 Protein folding
R-HSA-392499 Metabolism of proteins
R-HSA-422475 Axon guidance
R-HSA-445144 Signal transduction by L1
R-HSA-5205647 Mitophagy
R-HSA-556833 Metabolism of lipids
R-HSA-5633007 Regulation of TP53 Activity
R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation
R-HSA-6807070 PTEN Regulation
R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
R-HSA-68877 Mitotic Prometaphase
R-HSA-68886 M Phase
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-8878171 Transcriptional regulation by RUNX1
R-HSA-8934903 Receptor Mediated Mitophagy
R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
R-HSA-8948751 Regulation of PTEN stability and activity
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9612973 Autophagy
R-HSA-9663891 Selective autophagy
R-HSA-9675108 Nervous system development
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028960 BXGD002101 Oligospermia Male Urogenital Diseases
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0037286 BXGD002681 Skin Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0206042 BXGD004145 Fatal Familial Insomnia Infections; Nervous System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0375023 BXGD007970 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0595989 BXGD009632 Carcinoma of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0751254 BXGD010366 Creutzfeldt-Jakob Disease, Familial Infections; Nervous System Diseases; Mental Disorders
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332079 BXGD012486 Anaplastic Large Cell Lymphoma, ALK-Positive Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000332 Fisetin 286.24
BXGC0000340 Kaempferol 286.24
BXGC0000436 Glycerol 92.09
BXGC0000622 Nicotinic acid 123.11
BXGC0000655 Harmalol 200.24
BXGC0001544 Harmaline 214.26
BXGC0001545 Harmine 212.25
BXGC0002018 Morin 302.24
BXGC0002071 Apigenin 270.24
BXGC0003705 Chloride 35.45
BXGC0004115 Norharman 168.19
BXGC0005683 Quercetin 302.24
BXGC0006193 Ellagic acid 302.19
BXGC0006306 Myricetin 318.24
BXGC0006635 Luteolin 286.24
BXGC0007014 Harman 182.22
BXGC0007029 Emodin 270.24
BXGC0012352 Chelerythrine 348.12
BXGC0018843 Quinalizarin 272.03
BXGC0024476 Lantic acid 470.34
BXGC0024554 D-luciferin 280
BXGC0034256 Rottlerin 516.18
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0049447 acetate 59.01
BXGC0051873 Sl-0101 516.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein