Showing entry for Ras-related protein Rab-4A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008564
Protein NameRas-related protein Rab-4A
Uniport IdP20338
GeneRAB4A
Gene Id5867
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019882 antigen processing and presentation
Biological Process GO:0006661 phosphatidylinositol biosynthetic process
Biological Process GO:0015031 protein transport
Biological Process GO:0032482 Rab protein signal transduction
Biological Process GO:0030100 regulation of endocytosis
molecular function GO:0001671 ATPase activator activity
molecular function GO:0051117 ATPase binding
molecular function GO:0019003 GDP binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0035255 ionotropic glutamate receptor binding
molecular function GO:0019905 syntaxin binding
cellular component GO:0098993 anchored component of synaptic vesicle membrane
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0005829 cytosol
cellular component GO:0031901 early endosome membrane
cellular component GO:0005768 endosome
cellular component GO:0070062 extracellular exosome
cellular component GO:0032593 insulin-responsive compartment
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0098837 postsynaptic recycling endosome
cellular component GO:0055038 recycling endosome membrane
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-HSA-1483255 PI Metabolism
R-HSA-1483257 Phospholipid metabolism
R-HSA-162582 Signal Transduction
R-HSA-1660499 Synthesis of PIPs at the plasma membrane
R-HSA-199991 Membrane Trafficking
R-HSA-199991 Membrane Trafficking
R-HSA-392499 Metabolism of proteins
R-HSA-556833 Metabolism of lipids
R-HSA-5653656 Vesicle-mediated transport
R-HSA-5653656 Vesicle-mediated transport
R-HSA-597592 Post-translational protein modification
R-HSA-6806834 Signaling by MET
R-HSA-8854214 TBC/RABGAPs
R-HSA-8873719 RAB geranylgeranylation
R-HSA-8875656 MET receptor recycling
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-9007101 Rab regulation of trafficking
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0005956 BXGD000356 Bone Marrow Diseases Hemic and Lymphatic Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0014060 BXGD000882 Encephalitis, St. Louis Infections; Nervous System Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0030481 BXGD002228 Tropical Spastic Paraparesis Infections; Nervous System Diseases
C0037928 BXGD002713 Spinal Cord Diseases Nervous System Diseases
C0085278 BXGD003150 Antiphospholipid Syndrome Immune System Diseases
C0265780 BXGD005574 Congenital absence of lung Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0410000 BXGD008406 Overlap syndrome Skin and Connective Tissue Diseases; Immune System Diseases
C0677607 BXGD009721 Hashimoto Disease Endocrine System Diseases
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1955861 BXGD016611 T-Cell Large Granular Lymphocyte Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4290046 BXGD022507 trachomatis
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
BXGC0048845 Guanosine Triphosphate 522.99
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein