protein

Showing entry for Beta-adrenergic receptor kinase 1

General Target Information
BXGT Id	BXGT008625
Protein Name	Beta-adrenergic receptor kinase 1
Uniport Id	P21146
Gene	GRK2
Gene Id	282682
Domain	PH; Pkinase; RGS
Pfam	PF00169 PF00069 PF00615
Organism	Bos taurus (Bovine)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0060048	cardiac muscle contraction
Biological Process	GO:0002029	desensitization of G protein-coupled receptor signaling pathway
Biological Process	GO:0007213	G protein-coupled acetylcholine receptor signaling pathway
Biological Process	GO:0002031	G protein-coupled receptor internalization
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway
Biological Process	GO:0007507	heart development
Biological Process	GO:0006886	intracellular protein transport
Biological Process	GO:1901081	negative regulation of relaxation of smooth muscle
Biological Process	GO:0045988	negative regulation of striated muscle contraction
Biological Process	GO:0003108	negative regulation of the force of heart contraction by chemical signal
Biological Process	GO:0018105	peptidyl-serine phosphorylation
Biological Process	GO:0018107	peptidyl-threonine phosphorylation
Biological Process	GO:1903566	positive regulation of protein localization to cilium
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway
Biological Process	GO:0006468	protein phosphorylation
Biological Process	GO:0009966	regulation of signal transduction
Biological Process	GO:0007217	tachykinin receptor signaling pathway
Biological Process	GO:0046718	viral entry into host cell
Biological Process	GO:0019079	viral genome replication
molecular function	GO:0031694	alpha-2A adrenergic receptor binding
molecular function	GO:0005524	ATP binding
molecular function	GO:0047696	beta-adrenergic receptor kinase activity
molecular function	GO:0031755	Edg-2 lysophosphatidic acid receptor binding
molecular function	GO:0004703	G protein-coupled receptor kinase activity
molecular function	GO:0004672	protein kinase activity
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005829	cytosol
cellular component	GO:0016020	membrane
cellular component	GO:0005886	plasma membrane
cellular component	GO:0045202	synapse

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002588	Magnesium		24.31

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}