Showing entry for Synaptotagmin-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008683
Protein NameSynaptotagmin-1
Uniport IdP21707
GeneSyt1
Gene Id25716
DomainC2
Pfam PF00168  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007420 brain development
Biological Process GO:0099502 calcium-dependent activation of synaptic vesicle fusion
Biological Process GO:0017156 calcium-ion regulated exocytosis
Biological Process GO:0048791 calcium ion-regulated exocytosis of neurotransmitter
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0005513 detection of calcium ion
Biological Process GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter
Biological Process GO:0007269 neurotransmitter secretion
Biological Process GO:0045956 positive regulation of calcium ion-dependent exocytosis
Biological Process GO:1903235 positive regulation of calcium ion-dependent exocytosis of neurotransmitter
Biological Process GO:1903861 positive regulation of dendrite extension
Biological Process GO:0033603 positive regulation of dopamine secretion
Biological Process GO:0050806 positive regulation of synaptic transmission
Biological Process GO:0031340 positive regulation of vesicle fusion
Biological Process GO:0051291 protein heterooligomerization
Biological Process GO:0017158 regulation of calcium ion-dependent exocytosis
Biological Process GO:0014059 regulation of dopamine secretion
Biological Process GO:1903305 regulation of regulated secretory pathway
Biological Process GO:0051966 regulation of synaptic transmission, glutamatergic
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
Biological Process GO:0051592 response to calcium ion
Biological Process GO:0061669 spontaneous neurotransmitter secretion
Biological Process GO:0048488 synaptic vesicle endocytosis
Biological Process GO:0016079 synaptic vesicle exocytosis
Biological Process GO:0071911 synchronous neurotransmitter secretion
Biological Process GO:0048278 vesicle docking
Biological Process GO:0016192 vesicle-mediated transport
molecular function GO:0005544 calcium-dependent phospholipid binding
molecular function GO:0048306 calcium-dependent protein binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0061891 calcium ion sensor activity
molecular function GO:0005516 calmodulin binding
molecular function GO:0030276 clathrin binding
molecular function GO:0042802 identical protein binding
molecular function GO:0050750 low-density lipoprotein particle receptor binding
molecular function GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
molecular function GO:0001786 phosphatidylserine binding
molecular function GO:0005543 phospholipid binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0000149 SNARE binding
molecular function GO:0017075 syntaxin-1 binding
molecular function GO:0030348 syntaxin-3 binding
molecular function GO:0019905 syntaxin binding
cellular component GO:0030424 axon
cellular component GO:0042584 chromaffin granule membrane
cellular component GO:0005737 cytoplasm
cellular component GO:0031045 dense core granule
cellular component GO:0060076 excitatory synapse
cellular component GO:0070382 exocytic vesicle
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005794 Golgi apparatus
cellular component GO:0030285 integral component of synaptic vesicle membrane
cellular component GO:0043229 intracellular organelle
cellular component GO:0043005 neuron projection
cellular component GO:0044306 neuron projection terminus
cellular component GO:0005886 plasma membrane
cellular component GO:0042734 presynaptic membrane
cellular component GO:0030141 secretory granule
cellular component GO:0008021 synaptic vesicle
cellular component GO:0030672 synaptic vesicle membrane
cellular component GO:0043195 terminal bouton
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0002708 Strontium 87.62
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein