Showing entry for DNA polymerase epsilon catalytic subunit A



                       
General Target Information
BXGT IdBXGT008710
Protein NameDNA polymerase epsilon catalytic subunit A
Uniport IdP21951
GenePOL2
Gene Id855459
DomainDNA_pol_B; DNA_pol_B_exo1; DUF1744
Pfam PF00136   PF03104   PF08490  
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006284 base-excision repair
Biological Process GO:0006287 base-excision repair, gap-filling
Biological Process GO:0006261 DNA-dependent DNA replication
Biological Process GO:0045004 DNA replication proofreading
Biological Process GO:0006302 double-strand break repair
Biological Process GO:0006303 double-strand break repair via nonhomologous end joining
Biological Process GO:0042276 error-prone translesion synthesis
Biological Process GO:0035822 gene conversion
Biological Process GO:0070868 heterochromatin organization involved in chromatin silencing
Biological Process GO:0031573 intra-S DNA damage checkpoint
Biological Process GO:0006272 leading strand elongation
Biological Process GO:0000278 mitotic cell cycle
Biological Process GO:0033314 mitotic DNA replication checkpoint
Biological Process GO:0007064 mitotic sister chromatid cohesion
Biological Process GO:0006297 nucleotide-excision repair, DNA gap filling
molecular function GO:0051539 4 iron, 4 sulfur cluster binding
molecular function GO:0003677 DNA binding
molecular function GO:0003887 DNA-directed DNA polymerase activity
molecular function GO:0003690 double-stranded DNA binding
molecular function GO:0003729 mRNA binding
molecular function GO:0000166 nucleotide binding
molecular function GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity
molecular function GO:0003697 single-stranded DNA binding
molecular function GO:0032183 SUMO binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0008622 epsilon DNA polymerase complex
cellular component GO:0005657 replication fork
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002374 Taurine 125.15
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein