protein

Showing entry for Prostaglandin G/H synthase 1

General Target Information
BXGT Id	BXGT008766
Protein Name	Prostaglandin G/H synthase 1
Uniport Id	P22437
Gene	Ptgs1
Gene Id	19224
Domain	An_peroxidase
Pfam	PF03098
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0019371	cyclooxygenase pathway
Biological Process	GO:0006954	inflammatory response
Biological Process	GO:0030216	keratinocyte differentiation
Biological Process	GO:0007612	learning
Biological Process	GO:0035633	maintenance of blood-brain barrier
Biological Process	GO:0007613	memory
Biological Process	GO:0097756	negative regulation of blood vessel diameter
Biological Process	GO:0032811	negative regulation of epinephrine secretion
Biological Process	GO:0010700	negative regulation of norepinephrine secretion
Biological Process	GO:0045987	positive regulation of smooth muscle contraction
Biological Process	GO:0045907	positive regulation of vasoconstriction
Biological Process	GO:0001516	prostaglandin biosynthetic process
Biological Process	GO:0006693	prostaglandin metabolic process
Biological Process	GO:0008217	regulation of blood pressure
Biological Process	GO:0042127	regulation of cell population proliferation
Biological Process	GO:0006979	response to oxidative stress
Biological Process	GO:0019233	sensory perception of pain
molecular function	GO:0051213	dioxygenase activity
molecular function	GO:0020037	heme binding
molecular function	GO:0046872	metal ion binding
molecular function	GO:0004601	peroxidase activity
molecular function	GO:0004666	prostaglandin-endoperoxide synthase activity
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005789	endoplasmic reticulum membrane
cellular component	GO:0005794	Golgi apparatus
cellular component	GO:0043231	intracellular membrane-bounded organelle
cellular component	GO:0005635	nuclear envelope
cellular component	GO:0001750	photoreceptor outer segment

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000663	Papain		206.28
BXGC0049738	Dexibuprofen		206.13
BXGC0049858	Chalcone		208.09
BXGC0052021	(R)-Ibuprophen		206.13

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}